A retrospective evaluation of the effect of oclacitinib (Apoquel) administration on development of surgical site infection following clean orthopedic stifle surgery.

The aim of this study was to determine the effect of oclacitinib (Apoquel) on development of surgical site infections in canines following clean orthopedic stifle surgery. Medical records of dogs undergoing unilateral, clean orthopedic stifle procedures were retrospectively examined for development of post-operative surgical site infections. Data collected for statistical analysis included age, sex, body weight, current medications, anesthesia and surgery times, white blood cell count, and neutrophil count. Surgical site infections were identified in 8.7% (34/390) of stifle procedures- 8.0% (29/364) in dogs not treated with oclacitinib and 19.2% (5/26) in dogs treated with oclacitinib (p = 0.053). There was a significant difference in development of surgical site infection in dogs with longer anesthesia times (p = 0.003) and higher body weights (p = 0.037). Dogs being treated with oclacitinib at the time of clean, orthopedic stifle surgery did not have a significantly higher incidence of surgical site infections. However, client education regarding risk of infection and increased patient monitoring post-operatively are recommended, especially in patients with increased body weight or longer anesthetic times.

Effects of a surgical checklist on decreasing incisional infections following foreign body removal from the gastrointestinal tract in dogs.

Two similar populations of dogs were evaluated in either a retrospective or prospective manner for 2 weeks after gastrointestinal foreign body surgery to determine the impact of a surgical checklist on the surgical site infection (SSI) rate. The medical records of 201 gastrointestinal foreign body surgeries were reviewed to determine the SSI rate without the use of a surgical checklist (SC-) and 101 consecutive gastrointestinal foreign body surgeries were performed using a surgical checklist (SC+). The SSI rate had a significant decrease from 19.9% to 11.9% with the use of the surgical checklist. When combining the cohorts, statistically significant predictors for development of an SSI following gastrointestinal foreign body removal included: a combined gastrotomy and enterotomy, an enterotomy, and known self-trauma.

Effets d'une liste de contrôle chirurgicale sur la réduction des infections des incisions après l'enlèvement d'un corps étranger dans le tube digestif des chiens. Deux populations semblables de chiens ont été évaluées, soit d'une manière rétrospective ou prospective, pendant 2 semaines après la chirurgie pour l'enlèvement d'un corps étranger afin de déterminer l'impact d'une liste de contrôle chirurgicale sur le taux d'infection du site chirurgical. Les dossiers médicaux de 201 chirurgies pour des corps étrangers gastro-intestinaux ont été examinés afin de déterminer le taux d'infection du site chirurgical sans le recours à une liste de contrôle chirurgicale et 101 chirurgies consécutives pour l'enlèvement d'un corps étranger ont été réalisées en utilisation une liste chirurgicale. Le taux d'infection du site chirurgical a connu une baisse significative de 19,9 % à 11,9 % avec le recours à une liste de contrôle chirurgicale. Lors de la combinaison des cohortes, les prédicteurs ayant une signification statistique pour le développement d'une infection au site chirurgical après l'enlèvement d'un corps étranger dans le tube digestif incluaient notamment : une gastrotomie et une entérotomie combinée, une entérotomie et un traumatisme auto-infligé connu.(Traduit par Isabelle Vallières).