Clinical Significance of Plasma CEA Levels in the Patients with Cervical Carcinoma during Follow-Up / 대한치료방사선과학회지

Carcinoembryonic antigen (CEA) has been studied in the field of gynecologic malignancy to determine whether it can be used as a tumor marker for early detection of recurrence or evaluation of therapeutic results. From January 1985 through December 1989, a total of 239 cervical cancer patients were entered for an analysis of plasma CEA level in the group with cervical cancer compared to the control group consisting of 65 normal healthy women and 18 women with benign gynecologic disease. Plasma CEA levels appear to be directly related with the tumor extension and as stages advance, the incidence of patients with abnormal plasma CEA levels is increased. Also, there seems to be a little higher incidence of abnormal CEA levels in patients with adenocarcinomas or adenosquamous carcinoma but not statistically significant because of small number of patients. When the patients developed recurrence, plasma CEA levels are markedly elevated in the majority, particularly in patients with hepatic metastases. In conclusion, serial plasma CEA checks could be used to detect recurrence during follow-up after treatment of cervical cancer.

Symptomatic Vertebral Hemangioma Treated by Radiotherapy: A Case Report / 대한치료방사선과학회지

Vertebral hemangiomas are rarely symptomatic and have been treated by surgical managements in patients with symptoms. A case of symptomatic vertebral hemangioma which was treated by radiotherapy successfully is presented.

Radical Radiotherapy of Head and Neck Cancer / 대한치료방사선과학회지

Sixty patients with head and neck carcinoma were studied retrospectively to assess the impact of treatment on survival and local control rate by stage in the Dept of Radiation Therapy, Korea University Had Wha Hospital between March 1981 and March 1986. Prior to definite radiotherapy, patients were evaluated by physical examination and radiologic studies including hest, paryngogram and CT scan and then these patients were grouped according to the American Joint Committee(AJC) staging system. They were Treated with RT alone or postoperative irradiation to the dose of 7,200 cGy/8 weeks and 6,000 cGy/7 weeks respectively. The results were obtained and as follows; 1. overall male to female sex ratio was 3.6:1. The peak age of patients with head and neck cancer was 6th decade. 2. In all patients treated by RT, the ratio of squamous cell carcinoma to non-squamous cell carcinoma was 3.5:1 (60/77 patients). 3. The incidence according to the anatomic site of primary tumor was 22 cases in the larynx, 12 cases in PNS, 7 cases in nasopharynx, 6 cases in oropharynx, and 3 cases in hypopharynx. 4. According to AJC staging system, 4 cases were Stage I, 7 in Stage II, 19 in Stage III and 27 in Stage IV. 5. The overall incidence of cervical lymph node metastases was 43% and subdigatric and submaxillary triangle lymph nodes were the most frequent site of metastases. 6. Local control was achieved in 48% of patients treated by radio-therapy. 7. The lung was the most common site for distant metastases, comprising 4 cases among 7 cases in which distant metastases occurred. 8. The overall estimated 5-year survival rate was 43% in the head and neck cancer treated with radiotherapy by life-table analysis.

Radiation Therapy of the Maxillary Sinus Lymphoma: A Case Report and Review of Literature / 대한치료방사선과학회지

Malignant lymphoma of the sinus is very rare but potentially radiocurable neoplasm. The disease is tend to be localized to the sinus and spread to adjacent local structure on initial presentation, and change to generalized lymphoma is uncommon. Most of sinus lymphoma is diffuse histiocytic type. Radiotherapy to the primary and neck nodes is the treatment of choice, and a survival rate of 50~70% can be expected.

Radiation Therapy of the Primary Ocular Melanoma: A Case Report and Review of Literature / 대한치료방사선과학회지

Intraocular melanoma is the most common primary occular malignancy in adult above the age of 20. Before treatment of intraocular melanoma, it is essential to do complete work-ps including LFT (LDH, SGPT), chest X-ay, whole body bone scan. Also, liver-pleen and brain scan will be done if clinically indicated. Though, malignant melanoma is radioresistant, however, show rapid tumor shrinkage after irradiation with total tumor dose of 7,000 to 8,000 rads in 7- weeks.

Preliminary Report of the Lung Cancer / 대한치료방사선과학회지

The preliminary analysis has been made of 73 patients who were treated in the Department of Radiation Therapy at Korea University Hospital for the lung cancer from April 1981 to December 1983. The patients were treated via Co-0 teletherapy unit and the doses were 5,400 rad/6 week for the curative, 3,600~4,500 rad/2 1/2~3 week for the palliative treatment. Thirty two (32/63=51%) patients have been for curative, 25/63 (40%) were for palliative, and 6/63 (9%) were for post-perative radiation. A post-adiation treatment, 28/63 (53%) were able to follow from 2 months to 3 yrs. During the follow up, chest X-ays and/or CT scans were taken and 22/27 (81.4%) of patients were responded more than 50% of tumor regression one month following completion of radiation.