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1.
Cureus ; 16(6): e62453, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-39015869

RESUMO

Introduction Adenoid tissue is part of the first line of immunity of the upper aero-digestive tract. It is located in the postero-superior wall of the nasopharynx behind the choana. Adenoid hypertrophy, a common childhood disorder, significantly contributes to the pathogenesis of otitis media with effusion (OME), which is the leading cause of hearing impairment in young children. This condition can result in delayed speech, poor academic performance, and language development issues. Assessing the size of the adenoids and their correlation with OME is crucial, as undiagnosed cases can lead to complications such as atelectasis of the tympanic membrane and cholesteatoma. Clinical examination of the nose alone is often insufficient, and children do not cooperate for nasal endoscopy. Therefore, a lateral radiograph of the skull is considered the most reliable method for assessing the adenoid size. The size of the adenoids can affect Eustachian tube patency, which is reflected in the results of impedance audiometry. This study aimed to correlate the size of adenoids with impedance audiometry findings. Methods This cross-sectional observational study was conducted in the Department of Otorhinolaryngology of a tertiary care hospital from October 1, 2022, to March 31, 2024. A sample size of 50 patients was taken for the study. The inclusion criterion of selection of the patients included patients aged 3 to 15 years, who suffered from recurrent attacks of upper respiratory tract infections, particularly those with adenoid facies confirmed by X-ray with a non-perforated tympanic membrane. Exclusion criteria encompassed patients below 3 or above 15 years, and those with acute or chronic suppurative otitis media, craniofacial anomalies, or nasal pathologies like polyps. Adenoids were graded using X-ray imaging of the nasopharynx, and correlations between the adenoid size and impedance audiometry findings, such as middle ear pressure and compliance, were analyzed.  Results The study assessed the relationship between the adenoid size and impedance audiometry findings, focusing on middle ear pressure and compliance, as well as the occurrence of OME. The results indicated a significant decline in middle ear pressure with increasing adenoid grades. Specifically, adenoid grade 1 had an average pressure of -3.50 daPa, while grade 4 had the lowest average pressure at -119.72 daPa. This trend was statistically significant with a p-value of 0.00042. Similarly, compliance values also decreased with higher adenoid grades. Grade 1 had an average compliance of 0.64 ml, whereas grade 4 had the lowest average compliance at 0.28 ml. This relationship was statistically significant, as indicated by a p-value of 0.0048. Additionally, the analysis showed that a significant majority of patients with enlarged adenoids also presented with OME, highlighting a strong association between adenoid hypertrophy and this condition. Conclusion The study concluded that larger adenoids were associated with lower middle ear pressure and reduced compliance. Additionally, a significant majority of patients with enlarged adenoids also had OME. This underscores the importance of evaluating adenoid hypertrophy in the context of OME due to its potential impact on childhood hearing and development.

2.
Indian J Otolaryngol Head Neck Surg ; 75(4): 3497-3500, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37974874

RESUMO

Objective: To study the efficacy of nanocrystalline silver in treating otitis externa. Methods: This is a retrospective study constituting 50 patients of 18 to 60 years, studied from July 2022 to February 2023, conducted in the outpatient clinic of a tertiary healthcare centre. Clinically diagnosed otitis externa patients were treated with fragmented gel foam coated with nanocrystalline silver gel and the response to this treatment was noted. Results: This study analysed a total of 50 cases of otitis externa in which the majority of patients fell between the age group of 30 to 45 years. Of the 50 patients included in the study, 30 were male and 20 were female. Pseudomonas aeruginosa was isolated in 50% of the patients followed by staphylococcus aureus in 36% of the patients. Among the 50 patients, 32 responded early to treatment (early responders), 15 were partial responders, and 3 did not respond to treatment (non-responders). Conclusion: Out of 50 patients, 32 responded early to treatment, 15 were partial responders, and 3 did not respond to treatment. The antimicrobial and anti-inflammatory properties of silver, particularly when used in the nanocrystalline form, have been shown to be highly effective in managing this condition. Further research is warranted to fully explore the potential of nanocrystalline silver in treating otitis externa and other related conditions.

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