RESUMO
Aim: The article explores the possibility of using nanoparticles and IgY technology together for biosensing and antibody delivery to fight mammalian infections. The use of IgG in passive immunotherapy has drawbacks; however, nanoparticles and IgY technology offer new opportunities for diagnostic and therapeutic applications. Methods: The primary selection of reports was based on the title and abstract, and potential studies were selected based on predefined inclusion criteria such as nanoparticle/nanomaterials and IgY, studies that have employed nanoparticles-IgY for diagnostic and therapeutic applications and animal experiments. Results: Nanoparticle-IgY conjugates have great potential in diagnostics and therapeutics, but translation of nanotechnology-based IgY technology from laboratory settings to clinical setup is still a challenge. As science advances, nanoimmunotherapy can be explored in modern-day medicine.
The human body makes proteins, called antibodies, that fight germs. Scientists use chickens and their eggs to make these proteins for treating diseases. If antibodies are used to treat diseases in the stomach, they can get damaged, but they can be protected with nanoparticles. They protect the proteins from degradation and deliver them safely to the target place. Thus, scientists use this combination to treat infections. The same combination also helps detect the germs.
