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Arch Pediatr ; 27(5): 261-264, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32409246

RESUMO

PURPOSE: Acute appendicitis is one of the commonest surgical emergencies in pediatrics. Treatment usually consists of a combination of surgery and antibiotics. The present study was designed to assess compliance with our local antibiotic protocol and analyse the consequences of non-compliance. METHODS: Children presenting with acute appendicitis between 2015 and 2017 were included in this study. The diagnosis of acute appendicitis was confirmed during surgery. Data concerning the antibiotic therapy received and infectious complications were reviewed. RESULTS: A total of 142 children with acute appendicitis were included. Antibiotic therapy complied with the protocol in 27.4% of cases, while an excessive duration of antibiotic therapy was observed in 65% of cases. A total of 270 days of non-recommended antibiotic therapy was noted; 32% of patients received a non-recommended combination of antibiotics. The infectious complications rate was 12.8% in the group of patients receiving appropriate antibiotic therapy, and 11.6% in the group with non-compliance to the protocol. No statistically significant difference between the groups was found (P=0.85). CONCLUSION: Poor compliance with the antibiotic guidelines for appendicitis resulted in antibiotic overuse with no benefit in terms of anti-infective efficacy. Better information for the medical team and repeated evaluation of our practices are essential.


Assuntos
Antibacterianos/uso terapêutico , Gestão de Antimicrobianos/normas , Apendicite/tratamento farmacológico , Fidelidade a Diretrizes/estatística & dados numéricos , Prescrição Inadequada/prevenção & controle , Uso Excessivo dos Serviços de Saúde/prevenção & controle , Doença Aguda , Adolescente , Gestão de Antimicrobianos/estatística & dados numéricos , Apendicectomia , Apendicite/cirurgia , Criança , Pré-Escolar , Protocolos Clínicos , Terapia Combinada , Esquema de Medicação , Quimioterapia Combinada , Feminino , Humanos , Prescrição Inadequada/estatística & dados numéricos , Lactente , Recém-Nascido , Masculino , Uso Excessivo dos Serviços de Saúde/estatística & dados numéricos , Guias de Prática Clínica como Assunto , Estudos Retrospectivos , Resultado do Tratamento
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