RESUMO
Diarrhoea and dysentery caused by Shigella spp. are major public health concerns. Emerging multidrug resistance (MDR) in this pathogen further complicates this disease. Extended spectrum ß-lactamases (ESBLs) have been described in this pathogen, which significantly compromises the treatment options for shigellosis. The usual ESBLs seen are sulfhydryl variable (SHV)-type; cefotaximases (CTX-M) are very uncommonly detected. Here, we report a CTX-M type and AmpC-producing Shigella flexneri from a three-year-old boy residing in Central Kerala, South India.
Assuntos
Proteínas de Bactérias/metabolismo , Disenteria Bacilar/microbiologia , Shigella flexneri/enzimologia , Resistência beta-Lactâmica , beta-Lactamases/metabolismo , Antibacterianos/farmacologia , Pré-Escolar , Fezes/microbiologia , Humanos , Índia , Masculino , Testes de Sensibilidade Microbiana , Shigella flexneri/isolamento & purificaçãoAssuntos
Infecções por Alphavirus/epidemiologia , Vírus Chikungunya , Surtos de Doenças/estatística & dados numéricos , Adolescente , Infecções por Alphavirus/sangue , Infecções por Alphavirus/imunologia , Criança , Pré-Escolar , Feminino , Humanos , Imunoglobulina M/sangue , Incidência , Índia/epidemiologia , Lactente , MasculinoRESUMO
We followed 55 high risk newborns from birth till one year using Trivandrum Development Screening Chart (TDSC) and Denver Development Screening Test (DDST). We also assessed their muscle tone, vision and hearing. Babies were classified into mild, moderate, and severe risk groups using a scoring system. Babies with developmental delay were categorized as having mild, moderate, or severe delay. The risk score was significantly associated with the severity of developmental delay (Plt; 0.001). Abnormalities of tone were also associated with development delay (P< 0.001).
