[Frequency of detection the of Brugada syndrome signs in the course of ECG registration].

The aim of the study was to assess prevalence of the Brugada syndrome during carrying out ECG in the conditions of medico-sanitary division of a large industrial enterprise. Signs of the Brugada syndrome were found on 20 of 42779 ECGs (0.047%) registered during 1 year in patients aged 22-68 years. Type 2 syndrome was noted in 4 patients, others had type 2 of the syndrome. Men comprised 90% of patients. At 24 hour ECG monitoring paroxysm of nonsustained ventricular tachycardia was registered in 1 patient during night hours. Cases of sudden death were registered in families of 3 patients (all men older than 45 years). Four patients experienced syncopi clinical picture of which resembled more neurocardiogenic but not arrhythmic attacks. Thus prevalence of the Brugada syndrome in our population was quite low.

[Prognostication of the course of stable ischemic heart disease by exercise stress echocardiography]. / Prognozirovanie techeniia stabil'noi ishemicheskoi bolezni serdtsa s pomoshch'iu stress-ékhokardiografii.

We analyzed data from 549 patients (450 with high and 99 -- low pretest probability of ischemic events). Duration of observation was 12-42 (mean 20.1+/-11.6) months. End points were death, nonfatal myocardial infarction, and revascularization. Cox proportional hazards model was used for assessment of relationship between clinical-instrumental data and events. One year risk of cardiac death and nonfatal myocardial infarction was 3 and 15%, event free survival -- 95 and 66% for patients with negative and positive result of stress echocardiography, respectively. Besides local contractility disturbances total test duration less than 6 min was significantly related to prognosis of main events while left ventricular hypertrophy, amount of METs, development of angina during stress test, and hypertensive disease were predictors of combined end point (death, nonfatal myocardial infarction, or revascularization). Thus results of exercise stress echocardiography had high prognostic power in patients with ischemic heart disease.

[Diagnosis of coronary atherosclerosis using echocardiography with bicycle ergometry exercise]. / Diagnostika koronarnogo ateroskleroza s pomoshch'iu ékhokardiografii s fizicheskoi nagruzkoi na veloérgometre.

AIM: To determine sensitivity and specificity of stress echocardiography (SEC) in diagnosis of stenosing atherosclerosis of coronary arteries (CA), especially in patients recovered from Q-myocardial infarction. MATERIAL AND METHODS: The above sensitivity and specificity were studied in 75 patients (70 males and 5 females; mean age 53.7 +/- 7 years) with coronary atherosclerosis (CS). RESULTS: The sensitivity of impaired local contractility index (ILCI) in univessel lesion was 77.8%, in multivessel lesion--90.4%, specificity--85.7%. Sensitivity of other parameters studied was for development of an anginal episode 65.4%, increment of ejection fraction under 5%--63.9%, increased end systolic volume--61.1%, depression of ST segment--48.1%, increased end diastolic volume 38.9%. A total of 3 parameters had 100% sensitivity: impossible a > 5% rise of EF in response to exercise, an increase of end systolic and diastolic volumes, anginal attack (85.7%), ST depression (78.6%). CONCLUSION: Hemodynamic parameters must be assessed in the course of SECG for objectivization of the result and improvement of its specificity.