[Pharmacokinetic modeling in clinical practice: pefloxacin]. / Farmakokinetické modelovanie v klinickej praxi: pefloxacín.

Pharmacokinetic modelling allows to set up a therapeutic plan for administering a drug. The advances of this procedure are particularly remarkable in drugs discharged by the liver. The principles of this approach are presented and illustrated on the treatment with pefloxacin. The potential causes of the adverse effect of the drug observed in one patient of the series studied could thus be suggested.