RESUMO
Thymoma is a very rare tumour arising from thymus in the anterior mediastinum. A case of a spindle cell thymoma with Myasthenia gravis in a 34-year-old female who presented with difficulty in breathing and swallowing with shortness of breath is reported.
Assuntos
Miastenia Gravis/complicações , Timoma/complicações , Neoplasias do Timo/complicações , Adulto , Feminino , Humanos , Imuno-Histoquímica , Timoma/classificação , Timoma/diagnóstico por imagem , Timoma/metabolismo , Neoplasias do Timo/classificação , Neoplasias do Timo/diagnóstico por imagem , Neoplasias do Timo/metabolismo , Tomografia Computadorizada por Raios XRESUMO
OBJECTIVE: The study was carried out to determine the clinical and morphological presentation of actinomycosis and its association with malignancy and other opportunistic infections. MATERIAL AND METHODS: A prospective and retrospective study of cases was done from January 2001 to December 2006 (5 years) in the department of pathology. RESULT: Total 19 cases of actinomycosis were found during this period. Patients presented with discharging sinus and non-healing superficial abscess. Out of 19 cases, three cases were associated with malignancy, two cases were associated with aspergillosis while one case was clinically misdiagnosed as malignancy. All cases were diagnosed pathologically except a case of maxillary sinusitis which was initially suspected as fungal sinusitis by CT scan. Since actinomycosis is often misdiagnosed it is important to know the clinical presentation and morphological features of actinomycosis for correct management. CONCLUSION: The clinical features and histopathological findings of actinomycosis are important to understand for its correct diagnosis and better management of patient.
Assuntos
Actinomicose/epidemiologia , Actinomicose/diagnóstico , Adolescente , Adulto , Idoso , Criança , Feminino , Hospitais de Ensino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Nepal/epidemiologia , Estudos Prospectivos , Estudos Retrospectivos , Fatores SexuaisRESUMO
The electrocardiographic (E.C.G.) changes were evaluated in 54 patients of lepra reaction. Abnormalities of the E.C.G. observed were in the form of prolongation of QTc in 24 (44.44%), ST-T changes in a (16.66%), bundle branch block and ventricular extrasystoles in 2 each (3.70%). The mean QTc interval in 64 normal adults was 0.41 second (S.D. +/- 0.03, range 0.36 to 0.44 second). It was 0.44 second (S.D. +/- 0.05, range 0.38 to 0.52 second) in patients of lepra reaction. The difference in the QTc values in the two groups was statistically significant (P less than 0.01). The E.C.G. abnormalities in patients of lepra reaction appears to be due to myocardial involvement.
