[Permissible degree of reduction of diet caloricity for obese patients]. / Dopustimaia stepen' reduktsii kaloriinosti ratsiona dlia tuchnykh bol'nykh.

A study was made of the effects of diets with varying degree of caloricity reduction at the expense of the decreased content of carbohydrates and fat (1200, 600, 300 kcal and calorie-free "zero" diet) on some indicators of lipid, carbohydrate, protein and mineral metabolism comparatively to the patients' clinical status. A group of patients receiving the diet with a caloricity of 1800 kcal served as control. It was shown that the diet with an average reduction of caloricity (1200 kcal) may be applied to the treatment of obese patients for a long period of time both on in- and outpatient basis. The decrease permissible and such a diet may be indicated for a short period of time (1-1 1/2) months), diets with extremely reduced caloricity (300 kcal, "zero" diet) is not advisable), since such diets exert an adverse action on metabolic processes in the body.

[Specific and nonspecific cytolysis reactions in rheumatic patients with a low degree of activity in the process of combined treatment by a high-protein diet and drug preparations]. / Izuchenie reaktsii spetsificheskogo i nespetsificheskogo tsitoliza u bol'nykh revmatizmom s maloi stepen'iu aktivnosti v protesse kompleksnogo lecheniia vysokobelkovoi dietoi i medikamentoznymi preparatami.

Effect of therapy including high-protein diet and hormones on specific and nonspecific cytolysis was studied in patients with torpid and latent-running recurrent rheumatic carditis. The number of HeLa cells on which specific antigens (cardiac tissue extract, collagen, group C streptococcal nucleoproteid) were adsorbed significantly decreased on addition to the test target sensitized lymphocytes from the patients examined. As a result of therapy most patients showed the reduced activity of supernatants obtained from peripheral blood lymphocyte cultures that were incubated with specific antigens.

[Parameters of polynuclear cell activity in torpid and latent recurrent rheumocarditis in the process of treatment with a high-protein diet and drug preparations]. / Nekotorye parametry aktivnosti polinuklearov u bol'nykh vialo i latentno tekushchim vozvratnym revmokarditom v protsesse lecheniia vysokobelkovoi dietoi i medikamentoznymi preparatami.

The in vitro test of direct granulation of basophils affected by specific antigens (cardial tissue, acid-soluble fraction of collagen, streptococcal allergens) was investigated in the course of treating 41 patients (29 women and 12 men aged from 20 to 50 years) suffering from a little active rheumatic fever. The patients received a complex of therapeutic measures including high-protein diet (130-140 g protein) and drugs (1.5-2.0 g acetylsalicylic acid and 15 mg of prednisolone a day). As a result of the treatment all the patients improved and demonstrated pain relief in the heart region, reduced palpitation, abatement of general weakness and fatigue. At the same time there was a decrease in the reactivity of basophilic leukocytes, shown by less number of degranulated cells in vitro, activated with specific antigens.

[Effect of diet therapy on the immunological indices in rheumatism]. / Vliianie dietoterapii na nekotorye immunologicheskie pokazateli u bol'nykh revmatizmom.

Rheumatic patients with torpid and latent course of the process were kept on a protein-rich diet (up to 140.0 g of protein). The effect of the diet on the organism was appraised by the peripheral blood lymphocytes blast-transformation reaction, as the one most comprehensively reflecting the immunological status of the individual. The patients were examined in dynamics, on admission to and at the time of discharge from the clinic. The data thus obtained suggest that the protein-rich diet tends to bring down the number of activated cells in in vitro cultures.

[Influence of an anti-atherosclerotic diet containing a protein enricher on the clinico-biochemical indices of patients with ischemic heart disease]. / Vliianie protivoateroskleroticheskoi diety, soderzhashchei belkovyi obogatitel', na kliniko-biokhimicheskie pokazateli bol'nykh ishemicheskoi bolezn'iu serdtsa.

Observations covered two groups of patients with ischemic heart disease (IHD). The first, control group (50 patients) received a course of treatment with antiatherosclerotic diet, while the second (50) was kept on a curative diet that included a protein enrichment agent. It was found that the patients of the lastly named group demonstrated, along with an improved general condition and diminution of basic clinical manifestation of IHD, a more noticeable fall of all the lipid fractions and also a more distinct and significant reduction of an elevated permeability of the capillaries to protein. The results obtained justify recommending inclusion of the protein enrichment agent in the diet of patients with IHD, to increase the biological value of the ration and the effect of the ongoing dietotherapy.