Shape-based Similarity Retrieval of Doppler Images for Clinical Decision Support.

Flow Doppler imaging has become an integral part of an echocardiographic exam. Automated interpretation of flow doppler imaging has so far been restricted to obtaining hemodynamic information from velocity-time profiles depicted in these images. In this paper we exploit the shape patterns in Doppler images to infer the similarity in valvular disease labels for purposes of automated clinical decision support. Specifically, we model the similarity in appearance of Doppler images from the same disease class as a constrained non-rigid translation transform of the velocity envelopes embedded in these images. The shape similarity between two Doppler images is then judged by recovering the alignment transform using a variant of dynamic shape warping. Results of similarity retrieval of doppler images for cardiac decision support on a large database of images are presented.

Characterizing spatio-temporal patterns for disease discrimination in cardiac echo videos.

Disease-specific understanding of echocardiographic sequences requires accurate characterization of spatio-temporal motion patterns. In this paper we present a method of automatic extraction and matching of spatio-temporal patterns from cardiac echo videos. Specifically, we extract cardiac regions (chambers and walls) using a variation of multiscale normalized cuts that combines motion estimates from deformable models with image intensity. We then derive spatio-temporal trajectories of region measurements such as wall motion, volume and thickness. The region trajectories are then matched to infer the similarities in disease labels of patients. Validation results on patient data sets collected from many hospitals are presented.