RESUMO
This paper presents influence of selected prognostic factors on results of hypopharyngeal cancer radiotherapy used as only treatment in 97 patients irradiated in Centre of Oncology-Institute in Gliwice between 1980-1987. One-variant analysis showed statistically significant influence of gender, decrease of haemoglobin level during radiotherapy and higher T and N stages. Multivariant analysis demonstrated, that only locoregional status and treatment time has decisive importance on radiotherapy results. Thus, better results of treatment depend on lower T and N stages and correct radiotherapy time.
Assuntos
Neoplasias Hipofaríngeas/radioterapia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , PrognósticoRESUMO
The aim of this paper was to evaluate the group of 50 patients with cervical nodes metastases from unknown primary site treated between 1980-1995 in Maria Sk_odowska-Curie Memorial Institute of Oncology in Gliwice. There were 42 males and 8 females ranging in age from 26 to 85 years (median 60). 24 patients underwent combined therapy (surgery with postoperative radiotherapy), 22 underwent radiotherapy. Only 4 patients were treated with surgery alone. 3-years DFS rates were 59% in group treated with combined method, and 10% in group treated only with radiation therapy (p = 0.003). After a median follow up of 39 months 10 primary tumors were discovered--8 in head and neck region, 2 in lower respiratory tracts. DFS rate in group with discovered primary tumors was 40%.
Assuntos
Neoplasias de Cabeça e Pescoço/radioterapia , Neoplasias de Cabeça e Pescoço/cirurgia , Linfonodos/efeitos da radiação , Linfonodos/cirurgia , Neoplasias Primárias Desconhecidas , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Neoplasias de Cabeça e Pescoço/secundário , Humanos , Metástase Linfática , Masculino , Pessoa de Meia-IdadeRESUMO
Aim of this study is comparison of natural history between two subtypes of cancer: squamous and undifferentiated, which were localised in oro- and nasopharynx. Analysis has contained 175 patients with undifferentiatied and 510 patients with squamous cell cancers of oro- and nasopharynx, who were treated in Centre of Oncology--Institute branch Gliwice in 1980-1998. Presence of undiferentiated subtypes were bounded with shortening time of presence the symptoms of disease, most frequent exophytic type of infiltration than in squamous cancer with ulcerative--necrotic type of infiltration. Higher aggressiveness of undifferentiated cancer is based on higher frequency of distant and nodal metastases, metastases to contralateral nodes and higher percentage of conglomerates.