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Leg Med (Tokyo) ; 9(1): 33-7, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17150401

RESUMO

Mitochondrial DNA sequences of the hypervariable regions HV1 and HV2 were analyzed in 205 unrelated ethnic Malays residing in Singapore as an initial effort to generate a database for forensic identification purposes. Sequence polymorphism was detected using PCR and direct sequencing analysis. A total of 152 haplotypes was found containing 152 polymorphisms. Out of the 152 haplotypes, 115 were observed only once and 37 types were seen in multiple individuals. The most common haplotype (16223T, 16295T, 16362C, 73G, 146C, 199C, 263G, and 315.1C) was shared by 7 (3.41%) individuals, two haplotypes were shared by 4 individuals, seven haplotypes were shared by 3 individuals, and 27 haplotypes by 2 individuals. Haplotype diversity and random match probability were estimated to be 0.9961% and 0.87%, respectively.


Assuntos
Regiões Determinantes de Complementaridade/genética , DNA Mitocondrial/genética , Etnicidade/etnologia , Genética Populacional , Polimorfismo Genético , Impressões Digitais de DNA , Haplótipos , Humanos , Malásia/etnologia , Reação em Cadeia da Polimerase , Análise de Sequência de DNA , Singapura
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