Transition moment directions and selected spectroscopic properties of Ivabradine.

Based on the Kawski-Gryczynski method the value of angle ß=38° between absorption and fluorescence transition moments of Ivabradine was determined. Such a high value of ß is responsible for low emission anisotropy of Ivabradine in a rigid polyvinyl alcohol matrix and in anhydrous glycerol despite the elongated shape of the fluorophore. Selected steady-state and time-resolved spectroscopic results support the analysis.

Förster resonance energy transfer and trapping in selected systems: analysis by Monte-Carlo simulation.

Monte-Carlo simulation method is described and applied as an efficient tool to analyze experimental data in the presence of energy transfer in selected systems, where the use of analytical approaches is limited or even impossible. Several numerical and physical problems accompanying Monte-Carlo simulation are addressed. It is shown that the Monte-Carlo simulation enables to obtain orientation factor in partly ordered systems and other important energy transfer parameters unavailable directly from experiments. It is shown how Monte-Carlo simulation can predict some important features of energy transport like its directional character in ordered media.