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2.
Acta Haematol ; 93(2-4): 101-4, 1995.
Artigo em Inglês | MEDLINE | ID: mdl-7639049

RESUMO

Rare cases of low-grade lymphomas have been described in patients with human immunodeficiency virus (HIV) infection. However, this is the first reported case of mantle-cell lymphoma, a type of low-grade lymphoma, in a patient who also had HIV infection. Salient clinical features included lymphocytosis, lymphadenopathy, splenomegaly, and involvement of the bone marrow and meninges. The disease proved to be unusually aggressive and response to chemotherapy was insignificant. The patient survived only 4 months.


Assuntos
Linfoma Relacionado a AIDS , Linfoma não Hodgkin/etiologia , Adulto , Progressão da Doença , Evolução Fatal , Feminino , Humanos , Linfoma Relacionado a AIDS/patologia , Linfoma não Hodgkin/patologia , Masculino , Pessoa de Meia-Idade , Abuso de Substâncias por Via Intravenosa/complicações
3.
Urol Int ; 53(3): 176-8, 1994.
Artigo em Inglês | MEDLINE | ID: mdl-7544042

RESUMO

Late relapses are exceedingly uncommon in patients with pathologic stage (PS) I non-seminomatous germ cell tumors (NSGCT) of the testis treated with inguinal orchiectomy and retroperitoneal lymph node dissection (RPLND). We describe an unusual patient with PSI NSGCT who relapsed 40 months after surgery. The only evidence of recurrent disease was an elevated serum alpha-fetoprotein level, and complete remission was achieved following the prompt institution of combination chemotherapy. To our knowledge, this is the first report of a late relapse in PSI NSGCT of the testis manifested only as an elevated tumor marker.


Assuntos
Germinoma/patologia , Recidiva Local de Neoplasia/patologia , Neoplasias Testiculares/patologia , Testículo/patologia , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Germinoma/tratamento farmacológico , Germinoma/cirurgia , Humanos , Excisão de Linfonodo , Masculino , Estadiamento de Neoplasias , Orquiectomia , Neoplasias Testiculares/tratamento farmacológico , Neoplasias Testiculares/cirurgia , Fatores de Tempo , alfa-Fetoproteínas/análise
4.
Acta Haematol ; 89(3): 141-3, 1993.
Artigo em Inglês | MEDLINE | ID: mdl-8362602

RESUMO

Patients with hemosiderosis who also suffer from coexistent anemia may be unable to tolerate frequent phlebotomies needed for depletion of body iron stores. Chelation therapy, an alternative approach, may be unsuitable for some patients due to allergic reactions, poor response or intolerance of long-duration subcutaneous administration. The use of recombinant human erythropoietin in such patients could increase the hematocrit and improve exercise tolerance allowing for more frequent phlebotomies. We report the successful use of this combined approach in two such patients.


Assuntos
Anemia Refratária/terapia , Sangria , Eritropoetina/uso terapêutico , Hemossiderose/terapia , Idoso , Anemia Refratária/etiologia , Anemia Refratária/patologia , Terapia Combinada , Feminino , Hemossiderose/complicações , Hemossiderose/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Proteínas Recombinantes/uso terapêutico
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