RESUMO
In this paper the authors presented 20 cases of death of individuals diagnosed at Department of Forensic Medicine of Medical University of Gdansk in the years 1996-2001. In all cases carbamazepine was found in post-mortem material collected from the deceased during autopsy. 14 deaths resulted from intoxication after overdose of drugs for the purpose of committing suicide. In the other cases carbamazepine did not have on influence on the cause of death. The subject of the chemo-toxicological analysis were blood and urine samples and also specimens of the stomach with its contents, liver, kidney, brain and lung specimens collected during autopsy. TLC, GC-FID, GC-MS, TLC-UV were used as diagnostic tools. Determined carbamazepine concentrations fluctuated between 1.5 to 78.6 micrograms/ml in the blood.
Assuntos
Analgésicos não Narcóticos/intoxicação , Anticonvulsivantes/intoxicação , Carbamazepina/intoxicação , Detecção do Abuso de Substâncias/métodos , Adulto , Autopsia , Química Encefálica , Overdose de Drogas/sangue , Overdose de Drogas/urina , Feminino , Medicina Legal/educação , Humanos , Intestinos/química , Rim/química , Fígado/química , Pulmão/química , Masculino , Pessoa de Meia-Idade , Polônia , Estômago/química , Toxicologia/educaçãoRESUMO
In this paper the authors presented the group 2-ethoxyethanol intoxication of 8 young men aged between 20 to 22. 50-100 ml of pure compound (diluted with water) was administrated as a drink. In this paper symptoms of acute intoxication to this compound were presented. GC-FID and GC-MS were used as diagnostic tools. The obtained results were compared with the data from available literature.