RESUMO
Seventy-eight cases of pilomatricoma are reported. The unexpected findings are new lesions occurring in middle and old age; the lack of association with other diseases; and the large number of lesions located deep in the skin. As contemporary knowledge of the nature of this disorder is advancing, it is suggested that the eponymous title be abandoned.
Assuntos
Neoplasias Cutâneas/patologia , Adolescente , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Calcinose , Criança , Feminino , Fibrose , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Pele/patologiaAssuntos
Tumor Glômico/patologia , Neoplasias Cutâneas/patologia , Adolescente , Adulto , Idoso , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Four patients are described who developed granulomatous reactions in the red portions of their tattoos. Histopathological and immunofluorescence studies showed features of lichen planus. Mercury was identified in only one patient's lesion, and hypersensitivity to mercury was shown by patch testing in one other patient. Tattooing may provide a localised antigenic challenge resulting in spontaneously occurring lichen planus.
Assuntos
Dermatite de Contato/etiologia , Líquen Plano/etiologia , Tatuagem/efeitos adversos , Adulto , Dermatite de Contato/imunologia , Dermatite de Contato/patologia , Imunofluorescência , Humanos , Líquen Plano/imunologia , Líquen Plano/patologia , Masculino , Testes do EmplastroRESUMO
The mechanisms, clinical features and management of the various forms of urticaria are discussed. The importance of histamine receptors, complement and the kinin cascade are reviewed.
Assuntos
Urticária , Angioedema/genética , Proteínas do Sistema Complemento/metabolismo , Fator XII/metabolismo , Histamina/metabolismo , Antagonistas dos Receptores Histamínicos H1/uso terapêutico , Humanos , Calicreínas/antagonistas & inibidores , Cininas/metabolismo , Urticária/diagnóstico , Urticária/tratamento farmacológico , Urticária/etiologia , Urticária/metabolismoRESUMO
PIP: A case of erythema nodosum in a 26-year-old woman who took Minilyn for 3 years is reported. The occurrence of erythema nodosum corresponded to the periods of use and discontinuation of Minilyn; it was assumed that Minilyn was responsible for the condition. After a challenge with 4 unknown types of pills, 1 of which was Minilyn, the erythema nodosum did not recur. It is possible that desensitization to Minilyn had occurred in the meantime.^ieng
Assuntos
Anticoncepcionais Orais Combinados/efeitos adversos , Anticoncepcionais Orais/efeitos adversos , Eritema Nodoso/induzido quimicamente , Adulto , Etinilestradiol/efeitos adversos , Feminino , Humanos , Linestrenol/efeitos adversosRESUMO
The clinical features, diagnosis management, aetiology and inheritance of angiokeratoma corporis diffusum (Fabry's disease) are discussed and the literature reviewed. The treatment and knowledge generally of this rare condition have not greatly improved in 75 years.
