[Effect of individualized goal directed therapy on outcome after major sugery].

BACKGROUND: Goal directed therapy (GDT) is applied during the initial resuscitation of sepsis, known as early goal directed therapy (EGDT). Recent studies in major abdominal surgery suggested that anesthetic management with GDT may decrease morbidity and hospital stay. We have utilized GDT in major invasive surgery such as pancreatoduodenectomy in November 2009. METHODS: In the anesthetic management of pancreatoduodenectomy, 11 patients managed by GDT were compared concerning postoperative hospital stay with 11 patients managed by conventional methods retrospectively. In our GDT protocol, we have set targets in mean blood pressure, oxygen saturation, and stroke volume variation, which is more individualized for each one. With falls below the target, fluid infusion, blood transfusions, and circulatory agonists were administered. In the conventional protocol, anesthesiologist managed the use of anesthetic agents, fluid infusion, blood transfusion, and circulatory agonist, through the observation of the operative field, blood pressure, heart rate and urine output. RESULTS: Patients utilizing the GDT showed shorter postoperative hospital stay (group GDT; 21.8 days vs conventional group; 32.6 days. P<0.05). CONCLUSIONS: Anesthetic management with goal-directed therapy, may have contributed to shorter postoperative hospital stay.

[Anesthesia induction for patients with cervical spinal disease].

BACKGROUND: In the cases in which the flexibility of the patient's neck is limited, it is often difficult to achieve intubation. Fiberoptic intubation has been chosen for patients with arthroses. However, as it requires techniques, it has been difficult for inexperienced anesthesiologists. METHODS: Awake induction using AirWay Scope was performed for 8 patients with cervical spinal diseases. Midazolam, propofol or dexmedetomidine is selected as a sedative drug. RESULTS: Intubation was performed easily and safely without any complications in all cases. No patients had memories of intubation. CONCLUSIONS: Awake intubation using AirWay Scope for patients with cervical spinal diseases is a safe and useful anesthesia method. As dexmedetomidine causes no respiratory depression and can expect cooperation from patients, it may give safe and efficient sedation in awake intubation cases.