Large uterine myoma with erythropoietin messenger RNA and erythrocytosis.

BACKGROUND: Myomatous erythrocytosis syndrome (erythrocytosis associated with a uterine myoma) has multiple proposed etiologies, one of which is altered erythropoietin production. CASE: A 28-year-old woman, gravida 0, para 0, presented with a solitary, degenerated uterine myoma that was 34-36 weeks' gestational size and erythrocytosis. After GnRH agonist treatment and myomectomy, the tumor was analyzed by reverse transcription-polymerase chain reaction. Specific erythropoietin primer with erythropoietin messenger RNA was noted. CONCLUSION: Erythropoietin production by myomata might cause erythrocytosis in myomatous erythrocytosis syndrome.