RESUMO
Cefotiam (CTM) was intravenously given to 12 patients with infectious diseases in the field of otorhinolaryngology including 10 cases with chronic suppurative otitis media. Daily doses of CTM were 1 to 4 g. Clinical responses were excellent in 3 patients, good in 5, fair in 1 and poor in 3. The rate of overall clinical effectiveness was 67%. Staphylococcus species were most frequently isolated from the patients and all of them were eradicated by the CTM treatment. No side effects and no abnormal laboratory findings relating to the drug administration were observed.
Assuntos
Infecções Bacterianas/tratamento farmacológico , Cefotaxima/análogos & derivados , Otorrinolaringopatias/tratamento farmacológico , Adolescente , Adulto , Idoso , Infecções Bacterianas/microbiologia , Cefotaxima/administração & dosagem , Cefotaxima/uso terapêutico , Cefotiam , Criança , Avaliação de Medicamentos , Feminino , Humanos , Infusões Parenterais , Injeções Intravenosas , Masculino , Pessoa de Meia-Idade , Otorrinolaringopatias/microbiologiaRESUMO
The clinical effect of cefsulodin (CFS) on Pseudomonas species infections in otorhinolaryngologic field was studied in 10 patients. The overall clinical effectiveness was 80% (excellent 4, good 4, poor 2). The bacteriological response of CFS against Pseudomonas species was evaluated from 11 strains. Eradication rate of Pseudomonas species was 82%. In 1 case, body temperature was rised after injection. No abnormal laboratory findings, relating to the drug, were observed after treatment.
