[Immunological imbalance in the newborn infant and its correction in a system to prevent neonatal morbidity and infant mortality]. / Immunologicheskii disbalans novorozhdennogo i ego korrektsiia v sisteme preduprezhdeniia neonatal'noi zabolevaemosti i mladencheskoi smertnosti.

Immunological changes were examined in neonates having a different clinical status and varying effects of immunomodulation. The paper shows it expedient to use intravenous immunoglobulin as part of a package of measures to nurse premature neonates. A method for evaluating the responsiveness of immunocytes in the newborn has been developed, which is based on the determination of the equilibrium between activation-induced T-cell proliferation and apoptosis.

[Characteristics of the mitogenic activity of purified thymocyte growth factor]. / Kharakteristika mitogennoi aktivnosti ochishchennogo faktora rosta timotsitov.

Being purified by gel filtration and reverse phase HPLC the thymocyte growth factor from the supernatant of the cell line of intrathymic precursors of T-lymphocytes can stimulate the growth of splenocytes and thymocytes nonactivated by mitogen. Addition of suboptimal doses of mitogen or phorbol myristate acetate does not enhance the cell response to the thymocyte growth factor. The thymocyte growth factor in capable of stimulating the growth of thymocytes synergistically with interleukin-2, but the direct action of the thymocyte growth factor is not mediated by the production and reception of interleukin-2 and interleukin-4.