[The action of fenoptin on cAMP dynamics in the isolated guinea pig heart during contraction-relaxation]. / Deistvie fenoptina na dinamiku tsAMF v izolirovannym serdtse morskoi svinki v protsesse ee sokrasheniia--rasslebleniia.

The influence of finoptin and Ca2+ concentration decrease on cAMP dynamic during cardiac cycle in guinea pig isolated heart, activated by isadrin (3 x 10(-8) M), has been studied. In isadrin activation of adrenoceptors cAMP concentration increased by 50% during contraction and decreased during relaxation. Hypocalcium solution (0.15 mM) and finoptin decreased cAMP concentration and influenced its dynamic during cardiac cycle.