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6.
Gig Sanit ; (11): 66-7, 1991 Nov.
Artigo em Russo | MEDLINE | ID: mdl-1809646

RESUMO

In experiments with two tissue culture lines it was shown, that cytotoxicity of mercury (1) derivatives (measured by CL50) is lesser two times, than it was for mercury (2) derivates. No significant differences in cytotoxicity were noted by the cell morphology and monolayer mitosis activity coefficient studies. This demonstrates the equal toxicity and dangerous to both derivates.


Assuntos
Cloreto de Mercúrio/toxicidade , Compostos de Mercúrio , Mercúrio/toxicidade , Sulfatos/toxicidade , Animais , Linhagem Celular , Células Cultivadas/efeitos dos fármacos , Dose Letal Mediana , Camundongos , Células Vero/efeitos dos fármacos
7.
Vrach Delo ; (4): 89-92, 1991 Apr.
Artigo em Russo | MEDLINE | ID: mdl-1829563

RESUMO

Workers engaged in the production of inorganic manganese salts revealed lesions of the upper respiratory pathways (catarrhal and subatrophic rhinitis, pharyngitis, laryngitis), skin (contact and allergic dermatitis), cardiovascular disorders. They also showed changes of renal function,mineral metabolism,acid stability of erythrocytes. Activation of the B-system of immunity and allergization of the body are also observed.


Assuntos
Indústria Química , Nível de Saúde , Manganês/efeitos adversos , Exposição Ocupacional/efeitos adversos , Adulto , Poluentes Ocupacionais do Ar/efeitos adversos , Dermatite Ocupacional/induzido quimicamente , Dermatite Ocupacional/diagnóstico , Dermatite Ocupacional/epidemiologia , Feminino , Humanos , Masculino , Doenças Profissionais/induzido quimicamente , Doenças Profissionais/diagnóstico , Doenças Profissionais/epidemiologia , Exposição Ocupacional/estatística & dados numéricos , Ucrânia/epidemiologia
11.
Gig Tr Prof Zabol ; (4): 20-2, 1991.
Artigo em Russo | MEDLINE | ID: mdl-1879748

RESUMO

The workers engaged in the processing of the UP-671, UP-671D, UP-677, UP-680 and UP-682 epoxide resins are influenced by both initial and intermediate industrial products, as well as the resins' volatile components in MAC threshold concentrations. The workers engaged in major professions displayed upper respiratory allergic diseases, contact and allergic dermatitis, sensibilization to epichlorhydrine, staphylococci and kidney allergen. Euthyroid goiter was diagnosed in most workers, along with thriiodothyronine decrease in blood serum and a higher rate of chromosomal aberrations in lymphocytes. The experimental studies performed revealed moderate-degree toxicity in the resins, their cumulation properties, as well as allergenic, irritating, mutagenic and embryotoxic characteristics. Basing on the results of the study, the USSR Health Ministry adopted the working zone air MAC for the resins at the level of 0.5 mg/m3, vapours, 2nd degree of hazardousness.


Assuntos
Compostos de Epóxi/toxicidade , Resinas Epóxi/toxicidade , Adulto , Poluentes Ocupacionais do Ar/efeitos adversos , Poluentes Ocupacionais do Ar/toxicidade , Animais , Aberrações Cromossômicas , Perda do Embrião/induzido quimicamente , Compostos de Epóxi/efeitos adversos , Resinas Epóxi/efeitos adversos , Feminino , Humanos , Masculino , Doenças Profissionais/induzido quimicamente , Doenças Profissionais/diagnóstico , Exposição Ocupacional/efeitos adversos , Gravidez , Ratos
12.
Gig Tr Prof Zabol ; (1): 10-1, 1991.
Artigo em Russo | MEDLINE | ID: mdl-2060806

RESUMO

It was established that the major hazardous substances in cobalt acetate, chloride, nitrate and sulphate processing shops were the finished product's dusts (disintegration aerosol) in concentrations from 0.05 to 53 mg/m3 depending on the stage of the technological process. An analysis of morbidity with temporary disability and the rate of the workers' appliance for medical advice showed, among the major groups of industrial workers, particular prevalence of the upper respiratory tract diseases (rhinitis, pharyngitis, laryngitis) and the signs of irritation of the mucous in the eyes. ECG examinations revealed marked changes of varying severity in the myocardium among 40-58 percent of the workers in major professions.


Assuntos
Cobalto/efeitos adversos , Poeira/efeitos adversos , Doenças Profissionais/etiologia , Cardiopatias/induzido quimicamente , Cardiopatias/etiologia , Humanos , Higiene , Laringite/induzido quimicamente , Laringite/etiologia , Doenças Profissionais/induzido quimicamente , Doenças Profissionais/prevenção & controle , Faringite/induzido quimicamente , Faringite/etiologia , Rinite/induzido quimicamente , Rinite/etiologia
13.
Gig Tr Prof Zabol ; (8): 3-5, 1991.
Artigo em Russo | MEDLINE | ID: mdl-1839002

RESUMO

It was established that industrial shops engaged in zinc compounds' processing were characterized by considerable temperature shifts, relative humidity and air motion changes. In drying and packing shops, concentrations of the final product dusts were established at 0.8-2 mg/m3. The major occupational pathology was constituted by skin and upper respiratory tract diseases, including allergic and contact dermatitis, chronic pharyngitis, tonsillitis and rhinitis. Blood tests revealed B-lymphocytes: increases, circulating immune complexes and considerable levels of lymphocytic spontaneous blastotransformations. Erythrocytic acidic hemolysis was markedly changed, which proved disbalances in the system of red blood.


Assuntos
Acetatos/toxicidade , Poluentes Ocupacionais do Ar/toxicidade , Indústria Química/normas , Dermatite Ocupacional/induzido quimicamente , Eritrócitos/efeitos dos fármacos , Leucócitos/efeitos dos fármacos , Doenças Profissionais/induzido quimicamente , Medicina do Trabalho/normas , Faringite/induzido quimicamente , Tonsilite/induzido quimicamente , Acetatos/normas , Ácido Acético , Adulto , Contagem de Células Sanguíneas/efeitos dos fármacos , Eritrócitos/fisiologia , Hemólise/efeitos dos fármacos , Hemólise/fisiologia , Humanos , Leucócitos/fisiologia , Concentração Máxima Permitida , Pessoa de Meia-Idade , Ucrânia
14.
Vrach Delo ; (12): 90-3, 1990 Dec.
Artigo em Russo | MEDLINE | ID: mdl-2089818

RESUMO

The professional noxae for workers engaged in production of cobalt acetate, chloride, nitrate and sulfate is dust of the final product in the form of aerosol disintegration. The main professional pathology is manifested in hypertrophic defensive processes in the upper respiratory tract, in contact dermatitis, cardiac disorders of different severity grades. Clinico-biochemical investigations revealed a clear increase of the content of urea, rest nitrogen, glucose, cholesterol and electrolytes (sodium and potassium) in the blood.


Assuntos
Indústria Química , Cobalto/efeitos adversos , Nível de Saúde , Poluentes Ocupacionais do Ar/efeitos adversos , Poluentes Ocupacionais do Ar/análise , Poeira/efeitos adversos , Poeira/análise , Humanos , Doenças Profissionais/induzido quimicamente , Doenças Profissionais/diagnóstico , Análise e Desempenho de Tarefas , Ucrânia
16.
Gig Tr Prof Zabol ; (11): 18-20, 1990.
Artigo em Russo | MEDLINE | ID: mdl-2128293

RESUMO

The proposed study of the immunologic reactivity state in chemical plant workers revealed humoral and cellular reactivity changes caused by chemical agents and the workers' immunologic background. It was established that cobalt and manganese salts caused initial immune response.


Assuntos
Autoanticorpos/análise , Indústria Química , Cobalto/imunologia , Imunoglobulinas/análise , Manganês/imunologia , Medicina do Trabalho , Tiocianatos/imunologia , Tioureia/imunologia , Testes de Hemaglutinação , Humanos , Ucrânia
17.
Gig Tr Prof Zabol ; (12): 26-30, 1990.
Artigo em Russo | MEDLINE | ID: mdl-2096087

RESUMO

It was established that the major hazardous factor in nitrate, sulphate and manganese basic carbonate processing shops was the dust of the final product. Upper respiratory tract (catarrhal, subatrophic rhinitis, pharyngitis, laryngitis), skin (allergic and contact dermatitis) and cardiac disorders were specified as the predominant pathology among manganese compounds processing shop workers. Mineral exchange disorders, lowered glucose content in the blood and violation in the acid persistence of the erythrocytes were revealed through medical examinations.


Assuntos
Indústria Química , Manganês/efeitos adversos , Doenças Profissionais/induzido quimicamente , Adulto , Aberrações Cromossômicas , Feminino , Humanos , Masculino , Doenças Profissionais/diagnóstico , Doenças Profissionais/imunologia
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