RESUMO
The title compounds, C17H13N3OS2, (I), and C17H12BrN3OS2, (II), are potential active pharmaceutical ingredients. Compound (I) comprises two almost planar fragments. The first is the central (carbamo-thio-yl)amide (r.m.s. deviation = 0.038â Å), and the second consists of the thia-zole and two phenyl rings (r.m.s. deviation = 0.053â Å). The dihedral angle between these planes is 15.17â (5)°. Unlike (I), compound (II) comprises three almost planar fragments. The first is the central N-(thia-zol-2-ylcarbamo-thio-yl)amide (r.m.s. deviation = 0.084â Å), and the two others comprise the bromo-phenyl and phenyl substituents, respectively. The dihedral angles between the central and two terminal planar fragments are 21.58â (7) and 17.90â (9)°, respectively. Both (I) and (II) feature an intra-molecular N-Hâ¯O hydrogen bond, which closes an S(6) ring. In the crystal of (I), mol-ecules form hydrogen-bonded layers parallel to (100) mediated by N-Hâ¯S and C-Hâ¯O hydrogen bonds. In the crystal of (II), mol-ecules form a three-dimensional framework mediated by N-Hâ¯Br and C-Hâ¯O hydrogen bonds, as well as secondary Sâ¯Br [3.3507â (11)â Å] and Sâ¯S [3.4343â (14)â Å] inter-actions.