Theta activity and cognitive functioning: Integrating evidence from resting-state and task-related developmental electroencephalography (EEG) research.

The theta band is one of the most prominent frequency bands in the electroencephalography (EEG) power spectrum and presents an interesting paradox: while elevated theta power during resting state is linked to lower cognitive abilities in children and adolescents, increased theta power during cognitive tasks is associated with higher cognitive performance. Why does theta power, measured during resting state versus cognitive tasks, show differential correlations with cognitive functioning? This review provides an integrated account of the functional correlates of theta across different contexts. We first present evidence that higher theta power during resting state is correlated with lower executive functioning, attentional abilities, language skills, and IQ. Next, we review research showing that theta power increases during memory, attention, and cognitive control, and that higher theta power during these processes is correlated with better performance. Finally, we discuss potential explanations for the differential correlations between resting/task-related theta and cognitive functioning, and offer suggestions for future research in this area.

Toddlers' affective responses to sociomoral scenes: Insights from physiological measures.

A growing literature suggests that preverbal infants are sensitive to sociomoral scenes and prefer prosocial agents over antisocial agents. It remains unclear, however, whether and how emotional processes are implicated in infants' responses to prosocial/antisocial actions. Although a recent study found that infants and toddlers showed more positive facial expressions after viewing helping (vs. hindering) events, these findings were based on naïve coder ratings of facial activity; furthermore, effect sizes were small. The current studies examined 18- and 24-month-old toddlers' real-time reactivity to helping and hindering interactions using three physiological measures of emotion-related processes. At 18 months, activity in facial musculature involved in smiling/frowning was explored via facial electromyography (EMG). At 24 months, stress (sweat) was explored via electrodermal activity (EDA). At both ages, arousal was explored via pupillometry. Behaviorally, infants showed no preferences for the helper over the hinderer across age groups. EMG analyses revealed that 18-month-olds showed higher corrugator activity (more frowning) during hindering (vs. helping) actions, followed by lower corrugator activity (less frowning) after hindering (vs. helping) actions finished. These findings suggest that antisocial actions elicited negativity, perhaps followed by brief disengagement. EDA analyses revealed no significant event-related differences. Pupillometry analyses revealed that both 18- and 24-month-olds' pupils were smaller after viewing hindering (vs. helping), replicating recent evidence with 5-month-olds and suggesting that toddlers also show less arousal following hindering than following helping. Together, these results provide new evidence with respect to whether and how arousal/affective processes are involved when infants process sociomoral scenarios.

Social versus non-social behavioral inhibition: Differential prediction from early childhood of long-term psychosocial outcomes.

Behavioral inhibition (BI) is a temperamental style characterized by cautious and fearful behaviors in novel situations. The present multi-method, longitudinal study examined whether young children's observed and parent-reported BI in social versus non-social contexts predicts different long-term psychosocial outcomes. Participants (N = 279) were drawn from a longitudinal study of socioemotional development. BI in social contexts ("social BI") was measured via children's observed wariness toward unfamiliar adults and peers at 24 and 36 months and parents' reports of children's social fear/shyness at 24, 36, and 48 months. BI in non-social contexts ("non-social BI") was measured via children's observed fearful responses to masks and novel toys, and parents' reports of children's distress to non-social novelty at 9 months and non-social fear at 48 months. At 15 years, anxiety was assessed via adolescent- and parent-reports, and global internalizing and externalizing problems were assessed via parent-reports. Confirmatory factor analysis showed that a two-factor model fit the BI data significantly better than a single-factor model, providing evidence for the dissociation of BI in social versus non-social contexts. Social BI was uniquely associated with adolescent social anxiety, whereas non-social BI was specifically associated with adolescent separation anxiety. Neither social BI nor non-social BI predicted global internalizing and externalizing problems, providing evidence for the specific relations between BI and anxiety problems. Together, these results suggest that young children's inhibited responses in social versus non-social situations predict different subtypes of anxiety problems in adolescence, highlighting the multifaceted nature of BI and the divergent trajectories of different anxiety problems.

Resting brain activity in early childhood predicts IQ at 18 years.

Resting brain activity has been widely used as an index of brain development in neuroscience and clinical research. However, it remains unclear whether early differences in resting brain activity have meaningful implications for predicting long-term cognitive outcomes. Using data from the Bucharest Early Intervention Project (Zeanah et al., 2003), we examined the impact of institutional rearing and the consequences of early foster care intervention on 18-year IQ. We found that higher resting theta electroencephalogram (EEG) power, reflecting atypical neurodevelopment, across three assessments from 22 to 42 months predicted lower full-scale IQ at 18 years, providing the first evidence that brain activity in early childhood predicts cognitive outcomes into adulthood. In addition, both institutional rearing and later (vs. earlier) foster care intervention predicted higher resting theta power in early childhood, which in turn predicted lower IQ at 18 years. These findings demonstrate that experientially-induced changes in brain activity early in life have profound impact on long-term cognitive development, highlighting the importance of early intervention for promoting healthy development among children living in disadvantaged environments.

We aren't especially fearful apes, and fearful apes aren't especially prosocial.

Grossmann posits that heightened fearfulness in humans evolved to facilitate cooperative caregiving. We argue that three of his claims - that children express more fear than other apes, that they are uniquely responsive to fearful expressions, and that expression and perception of fear are linked with prosocial behaviors - are inconsistent with existing literature or require additional supporting evidence.

Multimodal study of the neural sources of error monitoring in adolescents and adults.

The ability to monitor performance during a goal-directed behavior differs among children and adults in ways that can be measured with several tasks and techniques. As well, recent work has shown that individual differences in error monitoring moderate temperamental risk for anxiety and that this moderation changes with age. We investigated age differences in neural responses linked to performance monitoring using a multimodal approach. The approach combined functional MRI and source localization of event-related potentials (ERPs) in 12-year-old, 15-year-old, and adult participants. Neural generators of two components related to performance and error monitoring, the N2 and ERN, lay within specific areas of fMRI clusters. Whereas correlates of the N2 component appeared similar across age groups, age-related differences manifested in the location of the generators of the ERN component. The dorsal anterior cingulate cortex (dACC) was the predominant source location for the 12-year-old group; this area manifested posteriorly for the 15-year-old and adult groups. A fMRI-based ROI analysis confirmed this pattern of activity. These results suggest that changes in the underlying neural mechanisms are related to developmental changes in performance monitoring.

Socially evaluative contexts facilitate mentalizing.

Our ability to understand others' minds stands at the foundation of human learning, communication, cooperation, and social life more broadly. Although humans' ability to mentalize has been well-studied throughout the cognitive sciences, little attention has been paid to whether and how mentalizing differs across contexts. Classic developmental studies have examined mentalizing within minimally social contexts, in which a single agent seeks a neutral inanimate object. Such object-directed acts may be common, but they are typically consequential only to the object-seeking agent themselves. Here, we review a host of indirect evidence suggesting that contexts providing the opportunity to evaluate prospective social partners may facilitate mentalizing across development. Our article calls on cognitive scientists to study mentalizing in contexts where it counts.

Infants' neural responses to helping and hindering scenarios.

A growing literature suggests infants prefer prosocial others over antisocial others. Although recent studies have begun to explore the neural mechanisms underlying these responses (Cowell and Decety, 2015; Gredebäck et al., 2015), these studies were based on relatively small samples and focused on distinct aspects of sociomoral responding. The current preregistered study systematically examined infants' neural responses both to prosocial/antisocial interactions and to prosocial/antisocial characters, using larger samples and two distinct age groups. We found that 6- (but not 12-) month-olds showed higher relative right frontal alpha power (indexing approach motivation) when viewing helping versus hindering scenarios. Consistent with past EEG work, infants showed no group-level manual preferences for the helper. However, analyses of infants' neural responses toward images of the helper versus hinderer revealed that both 6- and 12-month-olds showed differential event-related potential (ERP) responses in the P400 and N290 components (indexing social perception) but not in the Nc component (indexing attentional allocation), suggestive that infants' neural responses to prosocial versus antisocial characters reflect social processing. Together, these findings provide a more comprehensive account of infants' responses to prosocial/antisocial interactions and characters, and support the hypothesis that both motivational and socially relevant processes are implicated in infants' sociomoral responding.

Mechanisms of social evaluation in infancy: A preregistered exploration of infants' eye-movement and pupillary responses to prosocial and antisocial events.

Past research shows infants selectively touch and look longer at characters who help versus hinder others (Social evaluation by preverbal infants. Nature, 2007, 450, 557; Three-month-olds show a negativity bias in their social evaluations. Developmental Science, 2010, 13, 923); however, the mechanisms underlying this tendency remain underspecified. The current preregistered experiment approaches this question by examining infants' real-time looking behaviors during prosocial and antisocial events, and exploring how individual infants' looking behaviors correlate with helper preferences. Using eye-tracking, 34 five-month-olds were familiarized with two blocks of the "hill" scenario originally developed by Kuhlmeier et al. (Attribution of dispositional states by 12-month-olds. Psychological Science, 2003, 14, 402), in which a climber tries unsuccessfully to reach the top of a hill and is alternately helped or hindered. Infants' visual preferences were assessed after each block of 6 helping and hindering events by proportional looking time to the helper versus hinderer in an image of the characters side by side. Results showed that, at the group level, infants looked longer at the helper after viewing 12 (but not after viewing 6) helping and hindering videos. Moreover, individual infants' average preference for the helper was predicted by their looking behaviors, particularly those suggestive of an understanding of the climber's unfulfilled goal. These results shed light on how infants process helping/hindering scenarios, and suggest that goal understanding is important for infants' helper preferences.

Theory of mind in context: Mental-state representations for social evaluation.

Whereas Phillips and colleagues argue that knowledge representations are more basic than belief representations, we argue that an accurate analysis of what is fundamental to theory of mind may depend crucially on the context in which mental-state reasoning occurs. Specifically, we call for increased study of the developmental trajectory of mental-state reasoning within socially evaluative contexts.

The Homogeneity and Heterogeneity of Moral Functioning in Preschool.

The current study examined relations between distinct aspects of moral functioning, and their cognitive and emotional correlates, in preschool age children. Participants were 171 typically developing 3- to 6-year-olds. Each child completed several tasks, including (a) moral tasks assessing both performance of various moral actions and evaluations of moral scenarios presented both verbally and nonverbally; and (b) non-moral tasks assessing general cognitive skill, executive functioning, theory-of-mind, and emotion recognition. Shyness and empathic concern were assessed from video acquired during participation. Results demonstrated positive associations among distinct moral actions, as well as among distinct moral evaluation tasks, but few associations between tasks assessing moral actions and moral evaluation. Empathic concern and inhibitory control each emerged as important predictors of preschoolers' moral functioning.

Do infant sociomoral evaluation and action studies predict preschool social and behavioral adjustment?

Recent studies suggest that infants and toddlers evaluate others based on their prosocial and antisocial behaviors and engage in prosocial behaviors themselves. It is unknown to what extent infants' responses in such studies reveal stable individual differences in social and/or moral competence that persist throughout development. The current study (N = 63) demonstrates that infants' performance in sociomoral evaluation and action studies (mean age = 12 months) predicts social and behavioral adjustment at age 4 years. Specifically, a stronger preference for moral actions as an infant was associated with parent reports of fewer callous-unemotional traits, the domain most conceptually related to sociomoral evaluation and action, during preschool. Critically, preschool moral adjustment was uniquely associated with infants' sociomoral responding and not with other more general aspects of infant functioning. When 2 children with an autism spectrum disorder diagnosis were included in the sample, correlations between infant and preschool functioning were more widespread. Taken together, these results provide evidence for developmental continuity in the sociomoral domain and suggest that infants' early behavioral tendencies may be building blocks for subsequent sociomoral development.

Analogical Reasoning in Children With Autism Spectrum Disorder: Evidence From an Eye-Tracking Approach.

The present study examined analogical reasoning in children with autism spectrum disorder (ASD) and its relationship with cognitive and executive functioning and processing strategies. Our findings showed that although children with ASD were less competent in solving analogical problems than typically developing children, this inferior performance was attributable to general cognitive impairments. Eye-movement analyses revealed that children with ASD paid less attention to relational items and showed fewer gaze shifts between relational locations. Nevertheless, these eye-movement patterns did not predict autistic children's behavioral performance. Together, our findings suggest that ASD per se does not entail impairments in analogical reasoning. The inferior performance of autistic children on analogical reasoning tasks is attributable to deficits in general cognitive and executive functioning.

Aiming to complete the matrix: Eye-movement analysis of processing strategies in children's relational thinking.

The present study examines 5- to 8-year-old children's relation reasoning in solving matrix completion tasks. This study incorporates a componential analysis, an eye-tracking method, and a microgenetic approach, which together allow an investigation of the cognitive processing strategies involved in the development and learning of children's relational thinking. Developmental differences in problem-solving performance were largely due to deficiencies in engaging the processing strategies that are hypothesized to facilitate problem-solving performance. Feedback designed to highlight the relations between objects within the matrix improved 5- and 6-year-olds' problem-solving performance, as well as their use of appropriate processing strategies. Furthermore, children who engaged the processing strategies early on in the task were more likely to solve subsequent problems in later phases. These findings suggest that encoding relations, integrating rules, completing the model, and generalizing strategies across tasks are critical processing components that underlie relational thinking. (PsycINFO Database Record