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1.
Am J Dermatopathol ; 32(4): 387-91, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20514682

RESUMO

We herein present the clinicopathological features of an atypical cellular unguioblastic fibroma, a rare onychomatrical tumor, in an adult woman of Southeast Asian origin. The tumor displayed both diffuse hypercellularity and atypia in the mesenchymal component and the presence of large multinucleated cells with a ring-/floret-like arrangement of irregular and hyperchromatic nuclei. The mesenchymal cells displayed a patchy weak positive immunereactivity for CD34 (including atypical and wreath-like multinucleated cells) and for CD10 but were negative for low molecular weight cytokeratins, epithelial membrane antigen, CD68, factor XIIIa, smooth muscle actin, desmin, and HMB-45. The proliferative index as measured immunohistochemically (Mib-1/Ki-67) was 5%. The extent of these atypical histological features has not previously been described. One-year follow-up has been uneventful.


Assuntos
Fibroma/patologia , Doenças da Unha/patologia , Neoplasias Cutâneas/patologia , Feminino , Fibroma/metabolismo , Fibroma/cirurgia , Dedos/patologia , Dedos/cirurgia , Humanos , Imuno-Histoquímica , Pessoa de Meia-Idade , Doenças da Unha/metabolismo , Doenças da Unha/cirurgia , Neoplasias Cutâneas/metabolismo , Neoplasias Cutâneas/cirurgia
2.
J Hand Surg Am ; 34(1): 79-82, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19121733

RESUMO

Brachial plexus neuropathy can cause progressive pain and disability in patients with breast cancer. Metastatic spread and radiation injury are the most common causes in these patients. We report a case of partial ulnar nerve transfer to the nerve to the biceps muscle to restore elbow flexion in a patient with combined radiation-induced and metastatic brachial plexopathy.


Assuntos
Neuropatias do Plexo Braquial/etiologia , Neuropatias do Plexo Braquial/cirurgia , Músculo Esquelético/inervação , Transferência de Nervo/métodos , Nervo Ulnar/cirurgia , Idoso , Neoplasias da Mama/patologia , Carcinoma/patologia , Carcinoma Ductal/secundário , Feminino , Humanos , Músculo Esquelético/cirurgia , Neoplasias do Sistema Nervoso Periférico/secundário , Lesões por Radiação/complicações
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