Life Satisfaction and Negative Affect Among Trans Men, Trans Women, and Nonbinary Individuals in a U.S. National Sample.

Purpose: Transgender and nonbinary individuals often have limited educational and economic resources, lack social capital such as family and community support, and face discrimination. These factors are likely to have negative consequences for subjective well-being of transgender individuals. Yet, there is limited research using a national sample and comparing trans women, trans men, and nonbinary individuals. This study examined the impact of social support, social belonging, transgender connectedness, and discrimination on trans and nonbinary individuals' life satisfaction and negative affect. Methods: We used data from TransPop 2016-2018, the first survey conducted on a national probability sample of the transgender population in the United States. We focused on measures of life satisfaction and negative affect and their predictors, including social belonging, transgender connectedness, and everyday discrimination. Results: We found that trans men, trans women, and nonbinary individuals had lower life satisfaction and higher negative affect than cisgender heterosexual individuals. Social belonging had a positive effect on trans men and trans women's life satisfaction, whereas it had a negative effect on trans men and nonbinary individuals' negative emotion. While family support had a positive effect on trans men's life satisfaction, social support had mixed effects on nonbinary individuals' life satisfaction and negative affect. Finally, everyday discrimination had a negative influence on life satisfaction although there was variation by gender identity and dependent measure. Conclusion: Different factors predicted life satisfaction and negative affect of trans men, trans women, and nonbinary people. Thus, a one-size-fits-all model of trans and nonbinary subjective well-being does not work.

Quantum Disordering of an Antiferromagnetic Order by Quenched Randomness in an Organic Mott Insulator.

The behavior of interacting spins subject to randomness is a longstanding issue and the emergence of exotic quantum states is among intriguing theoretical predictions. We show how a quantum-disordered phase emerges from a classical antiferromagnet by controlled randomness. ^{1}H NMR of a successively x-ray-irradiated organic Mott insulator finds that the magnetic order collapses into a spin-glass-like state, immediately after a slight amount of disorder centers are created, and evolves to a gapless quantum-disordered state without spin freezing, spin gap, or critical slowing down, as reported by T. Furukawa et al. [Phys. Rev. Lett. 115, 077001 (2015)]PRLTAO0031-900710.1103/PhysRevLett.115.077001 through sequential reductions in the spin freezing temperature and moment.

23-valent pneumococcal polysaccharide vaccine improves survival in dialysis patients by preventing cardiac events.

BACKGROUND: Immunodeficient patients are recommended to receive pneumococcal vaccination. However, there is limited evidence showing effectiveness of the polysaccharide vaccine. Polysaccharide vaccination has shown an association with cardiovascular event risk reduction. We assessed the efficacy of the 23-valent pneumococcal polysaccharide vaccine (PPSV23) in relation to the risk of hospitalization and death due to pneumonia and acute cardiac events. METHODS: The medical records of all dialysis patients attending our 8 study centers in 2010 were studied, and we selected 1038 consecutive patients. One-to-one propensity score matching was used to correct for potential selection bias in a PPSV23-vaccinated group versus a non-vaccinated group, and a total of 510 patients were identified for outcome analysis. Time to first admission, or deaths due to all-cause pneumonia or cardiac events until 2015 were compared between both groups. RESULTS: The all-cause death rate was significantly decreased in the PPSV23-vaccinated group, (hazard ratio [HR] 0.62, 95% confidence interval [CI]; 0.46-0.83, P = 0.002). All-cause death was considered to be a competing risk for the other outcomes. Further outcomes were evaluated by competing risk analysis adjusting for mortality. There was no statistically significant difference in the hospitalization rate for pneumonia; however, the hospitalization rate due to cardiac events was significantly lower in the PPSV23-vaccinated group than in the non-vaccinated group (HR 0.44, 95% CI; 0.20-0.96, P = 0.040). There was no statistically significant difference in the death rate due to pneumonia; however, the rate of cardiac death was significantly lower in the PPSV23-vaccinated group than in the non-vaccinated group (HR 0.36, 95% CI; 0.18-0.71, P = 0.003). CONCLUSIONS: The PPSV23 vaccination is associated with a good prognosis and a low-risk of cardiac events in dialysis patients; however, there was no evidence indicating enhanced protective efficacy against pneumonia, suggesting the PPSV23 vaccination might improve the prognosis by directly preventing cardiovascular events.

Detection of tumor cells of serous tubal intraepithelial carcinoma (STIC) in cervical smears and rapid development of the ovarian involvement: A case report.

Serous tubal intraepithelial carcinoma (STIC) has attracted attention as a precursor lesion of high-grade serous carcinoma (HGSC) of the ovary. We report the rare case of a woman in whom adenocarcinoma cells were detected in cervical smears and demonstrated to be derived from STIC in the fimbria. The patient was a 48-year-old woman, in whom cervical smears contained adenocarcinoma cells, but cervical conization did not reveal adenocarcinoma. Because the post-conization smears again demonstrated adenocarcinoma cells, hysterectomy with bilateral salpingectomy was performed 16 months after the first detection of adenocarcinoma cells in cervical smears. Histopathological examination demonstrated STIC in the fimbria of the left fallopian tube. Bilateral ovaries appeared grossly normal at that time, but oophorectomy, which was performed 3 months later, disclosed HGSC involving the surface of bilateral ovaries. Detection of carcinoma cells from STIC in cervical smears is of marked significance for the management of patients, and we should keep in mind the possibility that adenocarcinoma cells in cervical smears are derived from STIC. The postoperative outcome of patients with STIC is considered generally favorable, and the clinical course of the present patient, in whom HGSC involving the bilateral ovaries was found shortly after salpingectomy, is exceptional.

Anomalous metallic behaviour in the doped spin liquid candidate κ-(ET)4Hg2.89Br8.

Quantum spin liquids are exotic Mott insulators that carry extraordinary spin excitations. Therefore, when doped, they are expected to afford metallic states with unconventional magnetic excitations. Here, we report experimental results which are suggestive of a doped spin liquid with anomalous metallicity in a triangular-lattice organic conductor. The spin susceptibility is nearly perfectly scaled to that of a non-doped spin liquid insulator in spite of the metallic state. Furthermore, the charge transport that is confined in the layer at high temperatures becomes sharply deconfined on cooling, coinciding with the rapid growth of spin correlations or coherence as signified by a steep decrease in spin susceptibility. The present results substantiate the desired doped spin liquid and suggest a strange metal, in which the coherence of the underlying spin liquid promotes the deconfinement of charge from the layers while preserving the non-Fermi-liquid nature.It is expected that introducing charge carriers into an exotic quantum spin liquid state may lead to an unconventional metal but there are no clear realizations of a metallic spin liquid. Here, the authors present a spin liquid candidate that also shows evidence of strange metal behavior.

Sugar intakes from snacks and beverages in Japanese children.

While sugar intake is an important factor for obesity, diabetes and dental caries, sugars are also important energy sources, especially for rapidly growing children. Children like sugar-rich sweet foods. However, intake for Japanese children is not known due to a lack of studies and sugar composition data. This study was designed to determine sugar intakes from snacks and beverages in Japanese school children. A nutrition survey was conducted for 3 weekdays for 283 Japanese school children (7, 10 and 13 y old) in 8 prefectures from different areas of Japan. The methods for the survey were the weighing method for school lunches and the 24-h recall method for other foods. To estimate sugar intakes, the sugar composition table that was recently compiled by us for 135 beverages, cakes and other sweets was used. Height and weight were measured. They were similar to Japanese averages. Energy intakes were also similar to the results of the Japanese National Health and Nutrition Surveys. Sugar eaten outside meals was 24.7±15.5 g/d. From the National Health and Nutrition Surveys conducted in 2009, the mean sucrose intake from meals including some home-made cookies for 7-14-y-old children was 5.5 g/d, suggesting the mean total sugar intake of these children was about 30 g/d. This was within the range of FAO/WHO recommendation (less than 10% of energy intake, 49 g for these children. Mean intakes among age groups were not significantly different (p>0.05), but the intake for girls was lower than for boys in the oldest age group (p<0.05). Contributions of each sugar to total intake were sucrose 64%, fructose 14%, glucose 13% and lactose 9%. Fructose and glucose were mainly from isomerized sugar. Contributions of food groups to total intake were beverages 25%, baked goods 19% and ice cream 17%, respectively, covering 61% of all. In conclusion, we revealed that the average sugar intake of Japanese children was within the range of the FAO/WHO recommendation, though the effects of the kind of sugars on health remain to be clarified.

Short piston-cylinder pressure cells based on Ni-Cr-Al cylinders and their application to fragile materials.

In this decade, the performance of piston-cylinder pressure cells has been drastically improved by using robust materials such as nickel-chromium-aluminum and cobalt-nickel-chromium-molybdenum alloys to construct the inner cylinders. In this article, we present several experimental techniques for carrying out resistivity measurements under high pressure by applying the piston-cylinder devices based on the nickel-chromium-aluminum cylinders to fragile materials such as organics. These techniques are, in principle, applicable to measurements on any solid-state conductor. First, we introduce the construction of our piston-cylinder cells including two kinds of wired platforms for transport measurements. Second, we describe the construction of the platforms and the method of introducing the samples. After reporting test results for conventional materials such as ammonium fluoride, bismuth, and tellurium, lastly, we present examples of the successful application of our method to organic materials.

Antiferromagnetic fluctuations in the organic superconductor kappa-(BEDT-TTF)2Cu(NCS)_{2} under pressure.

We measured the 13C-NMR spectrum and T1 of the quasi-two-dimensional organic superconductor kappa-(BEDT-TTF)2Cu(NCS)_{2} under pressure. This material was thought to show a relationship between T_{c} and the effective cyclotron mass m_{c};{*}, obtained from the Shubnikov-de Haas (SdH) effect. We found that kappa-(BEDT-TTF)2Cu(NCS)_{2} behaved as a Fermi liquid at low temperature under all pressures, and antiferromagnetic fluctuations were expected. The pressure dependence of the Korringa factor is similar to that of the effective cyclotron mass m_{c};{*}, suggesting that antiferromagnetic fluctuations contribute to the superconductivity of this material. We also found that, under pressure, T;{*} was shifted to 150 K, the temperature characteristic of the shift from bad metal to good metal.

Examination of the charge-sensitive vibrational modes in bis(ethylenedithio)tetrathiafulvalene.

We reinvestigated the two C=C stretching modes of the five-membered rings of ET (ET = bis(ethylenedithio)tetrathiafulvalene), namely, nu(2) (in-phase mode) and nu(27) (out-of-phase mode). The frequency of the nu(27) mode of ET(+) was corrected to be approximately 1400 cm(-1), which was identified from the polarized infrared reflectance spectra of (ET)(ClO(4)), (ET)(AuBr(2)Cl(2)), and the deuterium- or (13)C-substituted compounds of (ET)(AuBr(2)Cl(2)). It was clarified from DFT calculations that the frequency of the nu(27) mode of the flat ET(0) molecule was significantly different from that of the boat-shaped ET(0) molecule. We obtained the linear relationship between the frequency and the charge on the molecule, rho, for the flat ET molecule, which was shown to be nu(27)(rho) = 1398 + 140(1 - rho) cm(-1). The frequency shift due to oxidation is remarkably larger than that reported in previous studies. The fractional charges of several ET salts in a charge-ordered state can be successfully estimated by applying this relationship. Therefore, the nu(27) mode is an efficient probe to detect rho in the charge-transfer salts of ET. Similarly, a linear relationship for the nu(2) mode was obtained as nu(2)(rho) = 1447 + 120(1 - rho). This relationship was successfully applied to the charge-poor molecule of theta-type ET salts in the charge-ordered state but could not be applied to the charge-rich molecule. This discrepancy was semiquantitatively explained by the hybridization between the nu(2) and nu(3) modes.