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2.
Am Heart J ; 138(5 Pt 1): 934-40, 1999 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-10539826

RESUMO

BACKGROUND: A routine 12-lead electrocardiogram is commonly obtained to evaluate for possible acute myocardial infarction during the initial screening of patients with chest discomfort. Posterior myocardial infarction is commonly missed because it is not usually visible in the standard leads. In this study, we compared the sensitivity and specificity of posterior chest leads (V(7), V(8), and V(9)) and 12-lead electrocardiography in detecting posterior injury pattern during single-vessel percutaneous transluminal coronary angioplasty. METHODS AND RESULTS: Three posterior chest leads in addition to the routine 12-lead electrocardiogram were monitored simultaneously during single-vessel percutaneous transluminal coronary angioplasty of the right, circumflex, and left anterior descending coronary arteries in a total of 223 patients. Posterior injury patterns (95%) were detected mostly during circumflex coronary occlusion. Posterior leads were able to detect injury pattern in 49% (36 of 74) of patients, whereas the 12-lead electrocardiogram was able to detect only 32% (P <.04). When all 15 leads were used to detect all ST elevations, sensitivity increased to 57%, with a specificity of 98% for the circumflex coronary artery. If maximal ST depressions in leads V(2) to V(3) are considered to be from posterior myocardial injury, then the overall sensitivity is increased to 69%. CONCLUSIONS: Posterior leads significantly increased the detection of posterior injury pattern compared with the standard 12-lead electrocardiogram. Using all 15 leads significantly further improved the detection of circumflex coronary-related injury pattern over the standard 12-lead electrocardiogram.


Assuntos
Eletrocardiografia/métodos , Isquemia Miocárdica/diagnóstico , Angioplastia Coronária com Balão , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Isquemia Miocárdica/fisiopatologia , Isquemia Miocárdica/terapia , Sensibilidade e Especificidade
5.
Ann Emerg Med ; 20(5): 552-4, 1991 May.
Artigo em Inglês | MEDLINE | ID: mdl-2024796

RESUMO

Paroxysmal supraventricular tachycardia (PSVT) is seen somewhat frequently in the emergency department but less frequently during pregnancy. Although verapamil is widely used as the drug of choice for PSVT with a narrow QRS complex in a hemodynamically stable patient, the acute IV use of verapamil during pregnancy has not been well studied. Only a limited number of case reports document its safety and efficacy in the treatment of maternal or fetal PSVT. In general, the use of medication during pregnancy requires careful assessment of both the maternal and fetal risks versus benefits and documentation of patient consent. Because it crosses the placenta, one of the major concerns with the acute use of IV verapamil centers around the drug's potential effect on fetal heart rate. The case we present describes the occurrence of PSVT on two separate occasions in a woman in the third trimester of pregnancy. In both episodes, as much as 10 mg IV verapamil was given with resulting successful conversion to normal sinus rhythm. Fetal heart monitoring during drug administration failed to show significant change in fetal heart rate.


Assuntos
Complicações Cardiovasculares na Gravidez/tratamento farmacológico , Taquicardia Paroxística/tratamento farmacológico , Taquicardia Supraventricular/tratamento farmacológico , Verapamil/uso terapêutico , Adulto , Eletrocardiografia , Feminino , Frequência Cardíaca Fetal/efeitos dos fármacos , Humanos , Gravidez , Verapamil/efeitos adversos , Verapamil/farmacologia
6.
Cathet Cardiovasc Diagn ; 22(2): 127-9, 1991 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-1901244

RESUMO

Coronary artery aneurysms are not believed to have enough intact smooth muscle to generate significant vasoconstriction. A case is presented illustrating vasospasm of a large fusiform aneurysm of a right coronary artery during angioplasty. Pathophysiology of aneurysms is discussed.


Assuntos
Angioplastia Coronária com Balão , Aneurisma Coronário/fisiopatologia , Vasoespasmo Coronário/fisiopatologia , Idoso , Aneurisma Coronário/diagnóstico por imagem , Aneurisma Coronário/terapia , Angiografia Coronária , Vasoespasmo Coronário/prevenção & controle , Vasos Coronários/fisiopatologia , Humanos , Masculino , Nitroglicerina/uso terapêutico
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