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1.
Entropy (Basel) ; 20(9)2018 Aug 28.
Artigo em Inglês | MEDLINE | ID: mdl-33265732

RESUMO

When we examine the random growth of trees along a linear alley in a rural area, we wonder what governs the location of those trees, and hence the distance between adjacent ones. The same question arises when we observe the growth of metal electro-deposition trees along a linear cathode in a rectangular film of solution. We carry out different sets of experiments wherein zinc trees are grown by electrolysis from a linear graphite cathode in a 2D film of zinc sulfate solution toward a thick zinc metal anode. We measure the distance between adjacent trees, calculate the average for each set, and correlate the latter with probability and entropy. We also obtain a computational image of the grown trees as a function of parameters such as the cell size, number of particles, and sticking probability. The dependence of average distance on concentration is studied and assessed.

2.
Phys Med Biol ; 63(2): 025021, 2018 01 11.
Artigo em Inglês | MEDLINE | ID: mdl-29099727

RESUMO

The purpose of this study was to develop a straightforward method of supplementing patient anatomy and estimating out-of-field absorbed dose for a cohort of pediatric radiotherapy patients with limited recorded anatomy. A cohort of nine children, aged 2-14 years, who received 3D conformal radiotherapy for low-grade localized brain tumors (LBTs), were randomly selected for this study. The extent of these patients' computed tomography simulation image sets were cranial only. To approximate their missing anatomy, we supplemented the LBT patients' image sets with computed tomography images of patients in a previous study with larger extents of matched sex, height, and mass and for whom contours of organs at risk for radiogenic cancer had already been delineated. Rigid fusion was performed between the LBT patients' data and that of the supplemental computational phantoms using commercial software and in-house codes. In-field dose was calculated with a clinically commissioned treatment planning system, and out-of-field dose was estimated with a previously developed analytical model that was re-fit with parameters based on new measurements for intracranial radiotherapy. Mean doses greater than 1 Gy were found in the red bone marrow, remainder, thyroid, and skin of the patients in this study. Mean organ doses between 150 mGy and 1 Gy were observed in the breast tissue of the girls and lungs of all patients. Distant organs, i.e. prostate, bladder, uterus, and colon, received mean organ doses less than 150 mGy. The mean organ doses of the younger, smaller LBT patients (0-4 years old) were a factor of 2.4 greater than those of the older, larger patients (8-12 years old). Our findings demonstrated the feasibility of a straightforward method of applying supplemental computational phantoms and dose-calculation models to estimate absorbed dose for a set of children of various ages who received radiotherapy and for whom anatomies were largely missing in their original computed tomography simulations.


Assuntos
Neoplasias Encefálicas/radioterapia , Órgãos em Risco/efeitos da radiação , Imagens de Fantasmas , Fótons/uso terapêutico , Planejamento da Radioterapia Assistida por Computador/métodos , Adolescente , Neoplasias Encefálicas/diagnóstico por imagem , Criança , Pré-Escolar , Estudos de Coortes , Feminino , Humanos , Masculino , Método de Monte Carlo , Dosagem Radioterapêutica , Radioterapia Conformacional/métodos , Software , Tomografia Computadorizada por Raios X/métodos
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