RESUMO
The parameters of peripheral blood and hemopoietic organs in mature and immature bank voles inhabiting a chemically polluted area were studied. Variability of the blood system parameters depending on the level of toxic load and the animals' reproductive status was determined. Alteration of the cell composition of erythrocytes and leucocytes, the structure of erythrocytes, and the hemoglobin fractions and leucocyte functions describe the adaptive response to the factors of a changed environment more than the concentration of leucocytes, erythrocytes, and blood hemoglobin.
Assuntos
Células Sanguíneas/citologia , Exposição Ambiental/efeitos adversos , Metais Pesados/sangue , Adaptação Fisiológica , Animais , Arvicolinae , Células Sanguíneas/química , Análise Química do Sangue , Meio AmbienteRESUMO
Hematological and hematopoietic indices were studied in various seasons in bank vole in different reproductive states. The seasonal variation in the indices demonstrated patterns typical of each state and reflecting the adaptive response to changed habitat conditions.
Assuntos
Arvicolinae/sangue , Arvicolinae/crescimento & desenvolvimento , Estações do Ano , Animais , Testes Hematológicos , ReproduçãoRESUMO
The quantitative and structural hematological indices were studied in bank vole in different reproductive states (overwintered individuals, mature underyearlings, and immature underyearlings) in different years corresponding to different phases of the population cycle. The annual changes in certain hematological indices have been revealed for each reproductive state irrespective of the population cycle phase.
Assuntos
Envelhecimento/sangue , Arvicolinae/sangue , Estações do Ano , Animais , Arvicolinae/crescimento & desenvolvimento , Dinâmica Populacional , Federação RussaRESUMO
The preventive and medical effect of some nutrients of plant origin suggested as food supplement was studied in mice subjected to acute irradiation. The evidence of increased radioresistance was revealed.
Assuntos
Suplementos Nutricionais , Fitoterapia , Plantas Comestíveis/uso terapêutico , Lesões Experimentais por Radiação/prevenção & controle , Doença Aguda , Animais , Metabolismo Energético/efeitos dos fármacos , Metabolismo Energético/efeitos da radiação , Feminino , Masculino , Camundongos , Consumo de Oxigênio/efeitos dos fármacos , Consumo de Oxigênio/efeitos da radiação , Lesões Experimentais por Radiação/metabolismo , Proteção Radiológica/métodos , Irradiação Corporal TotalRESUMO
A number of quantitative morphological indices of blood system of two mice-like rodent species caught in radioactive contaminated areas was studied. Certain deviation in haemopoiesis and in blood characteristics were noted. The degree of deviations was not similar in the species with different radiosensitivity. It depends most probably on the total effect of the factors influenced animals in surroundings.
Assuntos
Arvicolinae/sangue , Muridae/sangue , Poluentes Radioativos/efeitos adversos , Animais , Contagem de Células Sanguíneas/efeitos da radiação , Ecologia , Feminino , Hematopoese/efeitos da radiação , Masculino , Tolerância a Radiação , Federação Russa , Especificidade da EspécieRESUMO
A study was made of acute toxicity and radioprotective efficiency of some heterocyclic isothiuronium analogues and their ability to change the oxygen uptake by the organism. The rate of hydrolysis of the preparations in vitro was determined. A correlation was found between the above-mentioned indices. On the basis of the data obtained it was concluded that aminothiol, formed as the result of enzymic digestion in the organism, was responsible for the radioprotective effect of the compounds under study since it reduced the oxygen uptake by the organism.