RESUMO
The concentration of insulin, high sensitivity C-reactive protein (CRP) and indices of lipid metabolism (concentrations of triacylglycerols, total cholesterol, cholesterol of low density lipoproteins and cholesterol of very low density lipoproteins) in women with concomitant obesity in the second trimester of pregnancy were studied. Changes of the lipid profile in the pregnant women with concomitant obesity indicate development of type IV hyperlipoproteinemia. Concentrations of insulin and CRP in the blood serum of the pregnant women with obesity were respectively 92.1% and 62.5% higher than in the control group. On the basis of literature data and our own research it was concluded that the complex of the metabolic changes (insulin resistance, dislipidemia, endothelial dysfunction, systemic inflammation) in pregnant women with obesity promotes development of proatherogenic changes.
Assuntos
Aterosclerose/etiologia , HDL-Colesterol/sangue , VLDL-Colesterol/sangue , Hiperlipoproteinemias/etiologia , Obesidade/complicações , Complicações Cardiovasculares na Gravidez/etiologia , Triglicerídeos/sangue , Adolescente , Adulto , Aterosclerose/sangue , Glicemia/análise , Estudos de Casos e Controles , Feminino , Humanos , Hiperlipoproteinemias/sangue , Obesidade/sangue , Gravidez , Complicações Cardiovasculares na Gravidez/sangue , Segundo Trimestre da Gravidez , Adulto JovemRESUMO
The experiment on 52 Wistar rats was made to study dependence of connective tissue reactions on typological properties of the body. The type of the reaction is closely related with the degree of changes in connective tissue structures of the digestive organs (periodontium, stomach) and the lungs. Acute stress stimulates degradation of the noncollagen proteins of the connective tissue main substance.
