RESUMO
Giant cell arteritis is a rare, poorly understood, and often misdiagnosed entity. A case is reported of giant cell arteritis in a 30-year-old white male who developed severe bilateral peripheral claudication affecting both legs. The erythrocyte sedimentation rate (ESR) was markedly elevated. The diagnosis of vasculitis was established by histology postoperatively following exploration of both superficial femoral arteries and the placement of a reversed saphenous vein bypass graft to the right leg. Biopsy of the temporal artery revealed no pathology. The patient has been completely asymptomatic postoperatively and has resumed all previous normal activities. This condition has persisted in spite of a failed graft determined by an arteriogram performed 3 months after surgery. He has been treated with steroids continuously since the procedure.
Assuntos
Artéria Femoral , Arterite de Células Gigantes/diagnóstico , Adulto , Biópsia , Doença Crônica , Artéria Femoral/diagnóstico por imagem , Artéria Femoral/patologia , Artéria Femoral/cirurgia , Arterite de Células Gigantes/patologia , Arterite de Células Gigantes/cirurgia , Oclusão de Enxerto Vascular/diagnóstico por imagem , Humanos , Claudicação Intermitente/diagnóstico , Claudicação Intermitente/patologia , Claudicação Intermitente/cirurgia , Masculino , Radiografia , Veia Safena/transplante , Artérias Temporais/patologia , UltrassonografiaRESUMO
We have discussed five lesions that are encounted less commonly than the usual occlusive carotid lesion that occurs at the carotid bifurcation, namely, high lesions, ulcerative plaques, tortuous carotids, carotid aneurysms, and carotid body tumors. Illustrative cases of these lesions were presented. The diagnostic difficulties related to some of them and the technicalaspects of their surgical management were discussed. New techniques for resecting internal carotid aneurysms and carotid body tumors by using autogenous saphenous vein grafts and a shunt were described and illustrated.
Assuntos
Arteriopatias Oclusivas/cirurgia , Doenças das Artérias Carótidas/cirurgia , Idoso , Aneurisma/cirurgia , Arteriopatias Oclusivas/diagnóstico por imagem , Doenças das Artérias Carótidas/complicações , Doenças das Artérias Carótidas/diagnóstico por imagem , Trombose das Artérias Carótidas/cirurgia , Tumor do Corpo Carotídeo/cirurgia , Transtornos Cerebrovasculares/etiologia , Criança , Feminino , Humanos , Ataque Isquêmico Transitório/etiologia , Masculino , Paraganglioma Extrassuprarrenal/cirurgia , Radiografia , Anormalidade Torcional , Úlcera/cirurgiaRESUMO
A case is reported of prolonged survival after pneumonectomy for anaplastic carcinoma of the left lung and excision of metastatic anaplastic carcinoma of the brain. The patient has survived for 8 years, 6 months after the lung surgery and 7 years after the brain surgery.
Assuntos
Neoplasias Encefálicas , Carcinoma de Células Escamosas , Neoplasias Pulmonares , Neoplasias Encefálicas/radioterapia , Neoplasias Encefálicas/cirurgia , Carcinoma de Células Escamosas/radioterapia , Carcinoma de Células Escamosas/cirurgia , Feminino , Humanos , Neoplasias Pulmonares/radioterapia , Neoplasias Pulmonares/cirurgia , Pessoa de Meia-Idade , Metástase Neoplásica , Fatores de TempoAssuntos
Sistema Límbico/metabolismo , Proteínas do Tecido Nervoso/biossíntese , Aminoácidos/metabolismo , Animais , Transporte Axonal , Encéfalo/metabolismo , Células Quimiorreceptoras , Citoplasma/metabolismo , Eletroforese em Gel de Poliacrilamida , Epitélio/metabolismo , Feminino , Genética , Cabras/imunologia , Cinética , Fígado/metabolismo , Pulmão/metabolismo , Camundongos , Septo Nasal , Neurônios/metabolismo , Bulbo Olfatório/metabolismo , Radioimunoensaio , Dodecilsulfato de Sódio , Membranas Sinápticas/metabolismo , Língua/metabolismo , TrítioRESUMO
A dose-response relation was established between prostaglandins and formation of adenosine 3',5'-monophosphate in the mouse ovary. The prostaglandin antagonist, 7-oxa-13-prostynoic acid, blocked the stimulatory effect of prostaglandin E(1), prostaglandin E(2), and luteinizing hormone on adenosine 3',5'-monophosphate formation in a competitive manner. Kinetic studies made it possible to suggest that there is a single luteinizing-hormone-related prostaglandin receptor in mouse ovaries, and that activation of this prostaglandin receptor is an essential requirement in the action of luteinizing hormone to stimulate adenosine 3',5'-monophosphate formation and steroidogenesis.
