Bioactivity of human dental pulp-derived stem cells with boron-controlled S-PRG filler eluate by anion exchange.

Surface pre-reacted glass-ionomer (S-PRG) filler is a bioactive glass filler capable of releasing various ions. A culture medium to which was added an S-PRG filler eluate rich in boron was reported to enhance alkaline phosphatase (ALP) activity in human dental pulp-derived stem cells (hDPSC). To clarify the role of boron eluted from S-PRG fillers, the modified S-PRG filler eluate with different boron concentrations was prepared by using an anion exchange material. Therefore, elemental mapping analysis of anion exchange material, adsorption ratio, hDPSCs proliferation and ALP activity were evaluated. For statistical analysis, Kruskal-Wallis test was used, with statistical significance determined at p<0.05. ALP activity enhancement was not observed in hDPSC cultured in the medium that contained the S-PRG filler eluate from which boron had been removed. The result suggested the possibility that an S-PRG filler eluate with controlled boron release could be useful for the development of novel dental materials.

Plasma concept for generating circularly polarized electromagnetic waves with relativistic amplitude.

Propagation features of circularly polarized (CP) electromagnetic waves in magnetized plasmas are determined by the plasma density and the magnetic field strength. This property can be applied to design a unique plasma photonic device for intense short-pulse lasers. We have demonstrated by numerical simulations that a thin plasma foil under an external magnetic field works as a polarizing plate to separate a linearly polarized laser into two CP waves traveling in the opposite direction. This plasma photonic device has an advantage for generating intense CP waves even with a relativistic amplitude. For various research purposes, intense CP lights are strongly required to create high energy density plasmas in the laboratory.