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1.
Biosecur Bioterror ; 3(1): 61-9, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15853456

RESUMO

In February 1999, the Maryland Department of Health and Mental Hygiene initiated pandemic influenza planning for the state of Maryland. This process involved several major steps, including the development of the Maryland Pandemic Influenza Preparedness Plan, and culminated in a high-level tabletop exercise to test the plan in April 2004. During the tabletop exercise, participants were presented with nine different fictitious scripts encompassing a single scenario. They were asked to respond to the information presented in each script, discuss organization-specific questions posed by the exercise facilitator, and make decisions regarding action steps that their organization would take in response to the various issues raised. The exercise identified a number of important gaps that need to be addressed, including (1) additional surge capacity specific to a pandemic, (2) greater understanding of the realities and implications of pandemic influenza among elected officials and decision-makers, (3) coordination of pandemic influenza planning with the existing emergency response infrastructure coupled with additional training in incident command, (4) further steps to operationalize several aspects of the Maryland Pandemic Influenza Preparedness Plan, and (5) additional federal guidance.


Assuntos
Surtos de Doenças/prevenção & controle , Implementação de Plano de Saúde/métodos , Influenza Humana/epidemiologia , Alocação de Recursos para a Atenção à Saúde/organização & administração , Humanos , Vírus da Influenza A , Influenza Humana/virologia , Maryland , Vacinação em Massa/organização & administração
2.
J Infect Dis ; 185(2): 133-46, 2002 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-11807686

RESUMO

Stool specimens from 156 Maryland nursing home residents, who became ill during 20 outbreaks of gastroenteritis from November 1987 through February 1988, were analyzed. All tested negative for astroviruses, enteroviruses, Group A rotaviruses, Sapporo-like caliciviruses, and enteric bacteria (i.e., Salmonella, Clostridium, and Shigella species). Eighty-two (52%) were positive for Norwalk-like viruses (NLVs), members of the family Caliciviridae. Six distinct genetic clusters within genogroups I and II of the NLVs were detected; a genogroup II (GII) virus closely related to the Camberwell virus in the NLV GII/4 genetic cluster was the predominant strain. Serologic evidence of infection with > or = 1 NLV was detected in 61 (56%) of 109 patients tested against 3 NLV antigens (i.e., Norwalk, Hawaii, and Toronto viruses). Sixteen (80%) outbreaks met the definition for an NLV outbreak. Taken together with a retrospective analysis of bacterial gastroenteritis in this same setting, these data support a major role for NLVs as etiologic agents of gastroenteritis in elderly persons.


Assuntos
Gastroenterite/etiologia , Norovirus/isolamento & purificação , Casas de Saúde , Idoso , Sequência de Aminoácidos , Anticorpos Antivirais/sangue , Capsídeo/genética , Ensaio de Imunoadsorção Enzimática , Gastroenterite/epidemiologia , Humanos , Maryland/epidemiologia , Dados de Sequência Molecular , Família Multigênica , Norovirus/genética , Fases de Leitura Aberta , Estações do Ano
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