1.
Clin Infect Dis
; 35(6): 769-72, 2002 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12203177
RESUMO
We conducted a trial of oral acetazolamide for the treatment of cryptococcal meningitis in 22 Thai adults with headache and an opening cerebrospinal fluid pressure of >/=200 mm H(2)0. The trial was terminated prematurely because patients who received acetazolamide developed significantly lower venous bicarbonate levels and higher chloride levels and had more-frequent serious adverse events than did subjects who received placebo.