RESUMO
The influence of deuterium depleted water with the modified isotope composition on an organism of animals is studied in physiological conditions and development of chronic endogenous intoxication of hepatorenal genesis. The influence of this water on isotope composition of plasma and tissues (the liver and kidneys) in laboratory animals is shown. The impact of this water on biochemical indicators (AST, ALT, alkaline phosphatase, creatinine, bilirubin) and dynamics in body weight of laboratory animals within 42 days is established. As a result of studies the possibility of the preventive use of deuterium depleted water for correction of metabolic processes is shown in various conditions of the functional system of the body's detoxification.
Assuntos
Peso Corporal , Deutério , Rim/metabolismo , Fígado/metabolismo , Plasma/metabolismo , Água/metabolismo , Animais , Biomarcadores/metabolismo , Masculino , Ratos , Ratos Wistar , Fatores de TempoRESUMO
Are investigated infringements of indicators antioxigion organism protection at hectare-stroenterology diseases at the patients living in territory of Krasnodarsky edge with various levels of pollution of an inhabitancy by pesticides and heavy metals. The ecological concept of an aetiology form chronic inflammatory diseases of bodies of digestive system which assumes the mechanism of decrease in resistance of an organism, development nonspetial the processes conducting to chronisation and complication of a current of diseases is considered.
Assuntos
Antioxidantes/metabolismo , Doenças do Sistema Digestório/etiologia , Monitoramento Ambiental , Poluentes Ambientais/toxicidade , Estresse Oxidativo/efeitos dos fármacos , Adolescente , Adulto , Estudos de Casos e Controles , Doença Crônica , Doenças do Sistema Digestório/sangue , Doenças do Sistema Digestório/induzido quimicamente , Poluentes Ambientais/sangue , Humanos , Hidrocarbonetos Clorados/sangue , Hidrocarbonetos Clorados/toxicidade , Metais Pesados/sangue , Metais Pesados/toxicidade , Pessoa de Meia-Idade , Praguicidas/sangue , Praguicidas/toxicidade , Federação Russa , Adulto JovemRESUMO
Are investigated infringements of indicators antioxigion organism protection at hectare-stroenterology diseases at the patients living in territory of Krasnodarsky edge with various levels of pollution of an inhabitancy by pesticides and heavy metals. The ecological concept of an aetiology form chronic inflammatory diseases of bodies of digestive system which assumes the mechanism of decrease in resistance of an organism, development nonspetial the processes conducting to chronisation and complication of a current of diseases is considered.
