Synthesis of Acid Mine Drainage (AMD) Sludge-Derived Al-Fe3O4 as Fenton-like Catalysts for the Efficient Degradation of Tetracycline.

In recent years, the development of environmentally friendly solid catalysts derived from sludge for the efficient removal of pollutants from wastewater has triggered widespread attention. Acid mine drainage (AMD) sludge is a waste produced in the process of acid mine wastewater treatment and contains multitudes of valuable metal resources. Hence it provides the original conditions for the synthesis of metal-based Fenton catalysts. In this article, the Fenton-like catalyst Al-Fe3O4 derived from AMD sludge was first synthesized by acid leaching coprecipitation methods, and the relationship among catalyst properties and pH, growth temperature, and growth time during coprecipitation was explored. Transmission electron microscope (TEM)/vibrating sample magnetometer (VSM)/particulate size description analyzer (DLS) results showed that the Al-Fe3O4 catalyst with high purity, large particle size, and strong magnetic properties was obtained under the conditions of pH 10, reaction temperature 60 °C, and growth for 45 min. In addition, the introduction of Al active sites promoted the activation of H2O2 and improved the catalytic activity of Al-Fe3O4, and the degradation efficiency of tetracycline was up to 93.9% within 60 min, which was 1.94 times that of pure Fe3O4. Moreover, Al-Fe3O4 exhibited excellent recyclability after four adsorption-desorption cycles. Hence, this study is expected to promote the resource utilization of industrial sludge and provide a new idea for the rapid removal of TC from aqueous solution.

A general electroelastic analysis of piezoelectric shells based on levy-type solution and eigenvalue-eigenvector method.

Eigenvalue-Eigenvector approach as well as Levy type solution are used for electroelastic analysis of a doubly curved shell made of piezoelectric material based on a shear deformable model and piezoelasticity relations. The electroelastic governing equations are derived using virtual work principle. The solution is proposed for a Levy type boundary conditions with two simply-supported boundary conditions and two clamped ones. After derivation of the governing equations, a solution satisfying two simply supported boundary conditions is assumed to arrive a system of ordinary differential equations. The latest governing equations are solved using Eigenvalue-Eigenvector method to satisfy clamped-clamped boundary conditions. The distribution of displacements, rotations, electric potential, strain and stress is presented along the planar coordinate. Accuracy of the proposed solution is justified through comparison with results of previous papers.

Characterization of Growth Secondary Hair in Min Pig Activated by Follicle Stem Cell Stimulated by Wnt and BMP Signaling Pathway.

In China, the national-level protected pig, the Min pig, is characterized by the development of secondary hairs and hair follicles in winter. Factors that dominate the genotype in the growth of secondary hairs are not clear through the concrete cell signaling pathways. This study compared hair phenotypes based on morphological structure, transcriptomics, and potential targeting molecules in the breeds of Min, Berkshire, and Yorkshire pigs. The results indicated that Min pigs have specific characteristics for the growth of secondary hairs compared with the Berkshire and Yorkshire pigs. The transcriptome analyses and quantitative reverse transcription-polymerase chain reaction results revealed that secondary hair growth was activated by follicle stem cells. The specific inhibitors of Wnt and BMP were studied using respective signals. The density of follicles, activity of follicle stem cells, and relative gene expression results have shown that Wnt and BMP stimulate the activity of follicle stem cells, and the Wnt signaling molecule has a significantly better effect than the BMP signaling molecule on stem cells. Wnt and BMP can promote the growth of local secondary hair and gene expression. Therefore, this study was conducted to verify the development mechanisms of secondary hairs, which have potential applications in laboratory animals and comparative medicine.

Association between the time-varying arterial carbon dioxide pressure and 28-day mortality in mechanically ventilated patients with acute respiratory distress syndrome.

BACKGROUND: Recent studies have shown an association between baseline arterial carbon dioxide pressure (PaCO2) and outcomes in patients with acute respiratory distress syndrome (ARDS). However, PaCO2 probably varies throughout the disease, and few studies have assessed the effect of longitudinal PaCO2 on prognosis. We thus aimed to investigate the association between time-varying PaCO2 and 28-day mortality in mechanically ventilated ARDS patients. METHODS: In this retrospective study, we included all adult (≥ 18 years) patients diagnosed with ARDS who received mechanical ventilation for at least 24 h at a tertiary teaching hospital between January 2014 and March 2021. Patients were excluded if they received extracorporeal membrane oxygenation (ECMO). Demographic data, respiratory variables, and daily PaCO2 were extracted. The primary outcome was 28-day mortality. Time-varying Cox models were used to estimate the association between longitudinal PaCO2 measurements and 28-day mortality. RESULTS: A total of 709 patients were eligible for inclusion in the final cohort, with an average age of 65 years, of whom 70.7% were male, and the overall 28-day mortality was 35.5%. After adjustment for baseline confounders, including age and severity of disease, a significant increase in the hazard of death was found to be associated with both time-varying PaCO2 (HR 1.07, 95% CI 1.03-1.11, p<0.001) and the time-varying coefficient of variation for PaCO2 (HR 1.24 per 10% increase, 95% CI 1.10-1.40, p<0.001) during the first five days of invasive mechanical ventilation. The cumulative proportion of exposure to normal PaCO2 (HR 0.72 per 10% increase, 95% CI 0.58-0.89, p = 0.002) was associated with 28-day mortality. CONCLUSION: PaCO2 should be closely monitored in mechanically ventilated ARDS patients. The association between PaCO2 and 28-day mortality persisted over time. Increased cumulative exposure to normal PaCO2 was associated with a decreased risk of death.