Immunologic alterations in the third trimester of pregnancy.

In a study carried out in a group of 61 pregnant women in the 21st to the 41st week of gestation and comparatively in 9 nonpregnant controls, the following were determined: changes in the leukocyte and lymphocyte count, proportion of T cell rosettes, T1 rosettes (TM cells), T2 rosettes (TG cells), EAC rosettes (B cells), EACD rosettes (killer cells), circulating NBT-positive phagocytes, serum IgG, IgA, IgM and C3 concentrations, 50% hemolytic activity of the complement system. The results are interpreted in the light of present data regarding the mechanisms of ovo-embryo-fetal allograft.

Metabolic investigations in persistent depressive states in the elderly.

In a group of 100 elderly patients with persistent depressive states, a series of investigations were carried out: hematologic, lipid, protein, energy metabolism hydroelectrolytic and acid-base balance, blood rheologic properties, immunologic, reactivity and certain humoral and regulation mechanisms. The results were compared with those obtained in two control groups, identical in number, the former in the third age without depressive states and the latter of healthy adults. The results were evaluated statistically. The results demonstrate that in depressive elderly subjects changes of the various parameters studied occur in the same direction as those in the group of elderly subjects without depression, but are far more accentuated.

The method of multilayer gel plates for the analytical immunochemical techniques.

A new analytical immunochemical method using gel film copies obtained by means of multilayer gel plates is described. The method is suitable for any variant of immunochemical gel technique. Perfect identity of the copies as well as some advantages are exemplified. In comparison with the already known monolayer gel plate method, the multilayer plate is more advantageous for the study of the dynamics of the antigen-antibody reaction, for the discovery of the nature of some unknown biological products available in very low quantities and for the discovery of the nature of some unknown biological products available in very low quantities and for the economy of certain costly reagents. Moreover, its high reproductibility recommends it as a reference method for the control of quality, especially of the precision and accuracy of the monolayer immunofiltration techniques.

[Influence of changes in the vegetative tonus on the effects of succinylcholine on blood pressure (experimental data)]. / Influenta variatiilor tonusului vegetativ asupra efectelor succinilcolinei care privesc presiunea sanguina (date experimentale)

Intravenous administration of small amounts (0,1 mg/kg of body weight) of succinyl-choline in dogs results in the increase of blood pressure through nicotine-like effects. The increase of succinyl-choline doses induces at first a lowering of the blood pressure through a muscarine-like effect, then its increase. Atropinization, as well as prealable vagotomy, prevents the lowering of the blood pressure but increases it through a nicotine-like effect. Neomistigmine increases both the nicotinic and the cholinergic (muscarinic) effects of succinyl-choline. The use of alpha-sympatico-mimetic drugs, followed by administration of succinyl-choline, generates hypertension and conjugation of alpha-sympatico-mimetic drugs with lepto-currarine induces hypotension, even when para-sympatic lysis has been performed in advance. Inhibition of the beta-sympatic components, followed by inhibition of the alpha-sympatic ones, prevents the development of the succinyl-cholinic hypotension. These facts indicate that the action of succinyl-choline on the blood pressure depends, to a considerable extent, on the condition of the central nervous system.