Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Nat Prod Res ; 34(22): 3299-3302, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30663391

RESUMO

Extracts from aerial parts of Prosopis ruscifolia, Bidens pilosa, Cercidium praecox and Phoradendron liga were assayed against toxigenic Aspergillus species. They were obtained by sequential extraction of the aerial parts with hexane (fHex), dichloromethane (fDCM), ethyl acetate (fEtOAc) and methanol (fMeOH). The fMeOH from P. ruscifolia showed the highest antifungal spectrum (MIC = 750-1500 µg mL-1; MID = 50-200 µg; DI = 1.7-3.0 mm). Indolizidine alkaloids (juliflorine and juliprosine) and tryptamine were identified with strong (MIC = 188 µg mL-1) and moderate antifungal activities (MIC = 750 µg mL-1), respectively, towards A. parasiticus and A. flavus. The fMeOH, the indolizidine alkaloids and tryptamine synergized the fungitoxic effect of potassium sorbate and propiconazole. They completely suppressed the biosynthesis of aflatoxins at concentrations of 47, 94 and 375 µg mL-1, respectively. Our results indicate that fMeOH and its identified alkaloids are promisory additives of commercial antifungals and are antiaflatoxigenic agents at concentrations below of those required for complete suppression of fungal growth.


Assuntos
Antifúngicos/farmacologia , Aspergillus/efeitos dos fármacos , Extratos Vegetais/farmacologia , Plantas/química , Aflatoxinas/metabolismo , Alcaloides/química , Alcaloides/farmacologia , Antifúngicos/química , Argentina , Aspergillus/metabolismo , Bidens/química , Avaliação Pré-Clínica de Medicamentos , Microbiologia de Alimentos , Fungicidas Industriais/química , Fungicidas Industriais/farmacologia , Indolizinas/farmacologia , Metanol/química , Testes de Sensibilidade Microbiana , Componentes Aéreos da Planta/química , Componentes Aéreos da Planta/metabolismo , Extratos Vegetais/química , Prosopis/química , Triptaminas/farmacologia
2.
Int J Food Microbiol ; 305: 108242, 2019 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-31176953

RESUMO

Fusarium meridionale and F. boothii cause Gibberella Ear Rot (GER) in maize. This study determined the effects of temperature (5-35 °C) and water activity (0.90-0.995 aw) on the growth, and deoxynivalenol (DON) and nivalenol (NIV) production of F. meridionale and F. boothii strains in maize grains. Fusarium graminearum sensu stricto strains from wheat were also tested. The three Fusarium species grew best at 0.995 aw and 25 °C. Growth was absent or marginal at 0.90 aw regardless of temperature. F. meridionale and F. boothii were sensitive to 30 °C and more affected by water stress than F. graminearum sensu stricto. The highest DON levels were at 0.995-0.97 aw and 30 °C and at 0.97 aw and 20 °C for F. graminearum sensu stricto, and at 0.995-0.97 aw and 20 °C for F. boothii. Fusarium meridionale reached maximum NIV accumulation at 0.995 aw and 20 °C. This produced DON at negligible levels compared to the other two Fusarium species. Growth of F. meridionale and F. boothii was well adapted to the usual autumn high humidity and mild temperatures associated with GER in northwest Argentina. Control strategies during grain development should be taken into account to reduce the risk of the presence of DON and NIV in the harvested grains.


Assuntos
Fusarium/metabolismo , Doenças das Plantas/microbiologia , Tricotecenos/metabolismo , Água/análise , Zea mays/microbiologia , Argentina , Fusarium/classificação , Fusarium/crescimento & desenvolvimento , Fusarium/isolamento & purificação , Umidade , Estações do Ano , Temperatura , Tricotecenos/análise , Triticum/química , Triticum/microbiologia , Água/metabolismo , Zea mays/química
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...