[Barrai's parameters for the Kirov oblast population and their geographic distribution].

The distribution of surnames in for populations of the district rank in Kirov oblast has been used to calculate Barrai's parameters, which are the following: Ir, 0.0008-0.0208; H, 6.80-11.57; v, 0.003-0.058; alpha, 47.35-1191.39; R, 23.03-50.07. The results have been compared with data on the 1980s; no substantial changes in the studied parameters during a generation have been found.

[Surname distribution and random inbreeding in Kirov oblast].

Data on surname distribution in 24 rations of Kirov oblast with a total adult population of more than 785000 people were used to calculate the random inbreeding values for populations of the district and rural municipality levels and analyze the geographic distributions of these values. The data have been compared with the results of studies carried out in the 1980s.

[Genetic epidemiological study of Bashkortostan Republic: the effect of genetic structure of population on the load of monogenic hereditary diseases].

Here we present the data obtained during medical genetic examination of the population of five districts of Bashkortostan Republic (Burzyanskii, Baimakskii, Abzelilovskii, Salavatskii, and Arkhangelskii) populated with 168050 persons including 135748 Bashkirs. The study involved all the population of the districts including each ethnic group and was conducted according to standard protocol developed in the Laboratory of Genetic Epidemiology, Medical Genetic Research Center, Russian Academy of Medical Sciences. Based on segregation analysis, the values of prevalence rates of the major types of Mendelian pathology (AD, AR, and X- linked diseases) was calculated in five regions of the Republic as well as for Bashkirs alone. Significant differences in the prevalence rates of AD and AR pathologies between individual districts, in particular upon division in rural and urban population, was observed. The prevalence rates comparison of monogenic hereditary pathology among Bashkirs compared to other previously examined populations have shown that the patterns of the hereditary disease load in the inspected districts of Bashkortostan were similar to that observed in the population of some districts in Udmurtia, Marii El and Chuvashiya. Russian European populations have shown significantly lower load of hereditary diseases. Correlation analysis of local inbreeding, endogamy and prevalence rates of AD and AR pathologies has shown that development of hereditary diseases load is significantly affected by gene drift.

[Marriage migration parameters in six rural districts of Bashkortostan Republic].

The marriage migration structure of the populations of six districts of Bashkortostan Republic has been studied. The rates of assortative marriages in Bashkirs, Tatars, and Russians are 1.02-2.71, 1.30-5.99, and 2.14-7.50, respectively; the endogamy indices are 0.58-0.97, 0.90, and 0.68, respectively. Malecot's isolation-by-distance parameters in Bashkirs, Tatars, and Russians, respectively, are the following: sigma is 6.7-83.0, 40.3-106.1, and 69.9; a is 0.00012-0.00074, 0.00170-0.0029, and 0.00096; and b is 0.0087-0.0467, 0.0038-0.0208, and 0.0129. Changes in these parameters with time have been traced.

[Analysis of reproductive and age parameters in Kalmyk rural populations].

Questionnaire data of 704 women of postreproductive age were used in this study. Questionnaire involved 462 Kalmyks, 119 Russians, 43 Kazakhs, 52 representatives of Northern Caucasus ethnic groups and, 28 other ethnic groups. The average number of pregnancies in Kalmyks was 5.49; the average number of live births was 3.21. The Crow index for Kalmyks was I(m) = 0.038, I(f) = 0.300, I(tot) = 0.350; and for Russians in Kalmykia, I(m) = 0.030, I(f) = 0.264, I(tot) = 0.302.

[Endogamy index and its changes with time in some populations of the Volga-Ural region].

Data on several populations of Russia have been used to demonstrate that the change in the endogamy index detected in the second half of the 20th century is not global. Migration activity remains high in populations with relatively low endogamy indices, and their endogamy does not change with time. In regions with medium and high endogamy indices, these values also tend to remain stable. The endogamy indices of urban populations are increasing, and those of rural populations are decreasing.