Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 29
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Vet Pathol ; 58(6): 1131-1141, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34269107

RESUMO

Recent reports have highlighted a lower-than-expected prevalence of neoplasia in elephants and suggested mechanisms for cancer resistance. But despite infrequent reports in the literature, uterine neoplasia is common in managed Asian elephants (Elephas maximus). This study is an archival review of reproductive tract neoplasia in 80 adult female Asian elephant mortalities in managed care facilities in the United States from 1988 to 2019. Neoplasms occurred in 64/80 (80%) of cases. Most were in the uterus (63/64; 98%) with only a single case of ovarian neoplasia. Myometrial leiomyomas were present in 57/63 (90%) cases with uterine neoplasia. Uterine adenocarcinoma was present in 8/63 (13%) cases. Remaining cases included endometrial adenoma (2), focal carcinoma in situ in endometrial polyps (1), anaplastic carcinoma (1), endometrial hemangioma (1), primitive neuroectodermal tumor (PNET; 1), and angiosarcoma (1). One case with uterine adenocarcinoma had a separate pelvic mass histologically characterized as an anaplastic sarcoma. Distant metastases were documented in 5/8 (63%) cases of uterine adenocarcinoma, and in the uterine anaplastic carcinoma, PNET, and angiosarcoma. Four uterine adenocarcinomas and one carcinoma in situ were examined immunohistochemically for pan-cytokeratin, vimentin, and estrogen receptor. In all, neoplastic cells were pan-cytokeratin positive and vimentin negative, and in 2 cases were immunoreactive for estrogen receptor. Results show that female reproductive tract neoplasia, particularly of the uterus, is common in Asian elephants and is not limited to leiomyomas. Importantly, uterine neoplasms have the potential to impact fecundity and may represent obstacles to conservation in managed care.


Assuntos
Carcinoma , Elefantes , Leiomioma , Neoplasias Uterinas , Animais , Carcinoma/veterinária , Feminino , Leiomioma/epidemiologia , Leiomioma/veterinária , Neoplasias Uterinas/veterinária , Útero
2.
Vet Clin Pathol ; 45(4): 584-593, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27870069

RESUMO

A 10-year-old castrated Domestic Short-Haired cat was presented to a primary care veterinarian for a wellness examination and laboratory examination for monitoring of diabetes mellitus. The CBC revealed marked thrombocytosis, leukopenia and macrocytic, normochromic anemia. The cat tested negative for FeLV and feline immunodeficiency virus, but was positive for Mycoplasma haemominutum by PCR. Hematologic abnormalities were not responsive to therapy, so a repeat CBC and a bone marrow aspiration for cytology were performed. Additional blood smear findings included anisocytosis with megaloblastic erythroid precursors, large platelets, eosinophilic myelocytes and metamyelocytes, and rare unidentified blasts. The bone marrow smear was highly cellular, and the cytologic pattern was consistent with myelodysplastic syndrome with an erythroid predominance. At that time, 15% blasts were present. The cat was treated with a vitamin K2 analog, doxycycline, and prednisolone, but without a clinical response. Within 3 months, euthanasia was elected due to declining quality of life, and a necropsy was performed. Postmortem bone marrow smears were highly cellular and dominated by monomorphic blasts of unknown line of origin (52%), persistent marked erythroid and megakaryocytic dysplasia, and ineffective erythropoiesis and granulopoiesis. Immunohistochemical, immunocytochemical, and cytochemical stains resulted in a diagnosis of acute myeloid leukemia of unclassified type. Additional histologic findings included mixed hepatitis with trematode infestation and lymphoplasmacytic interstitial nephritis with fibrosis. The marked thrombocytosis with myelodysplastic syndrome and the FeLV-negative status of this cat were unusual. The difficulty in classifying the myelodysplasia and subsequent leukemia highlights a need for further reporting and characterization of these types of disease.


Assuntos
Anemia Macrocítica/veterinária , Doenças do Gato/diagnóstico , Leucemia Mieloide/veterinária , Leucopenia/veterinária , Doenças Mieloproliferativas-Mielodisplásicas/veterinária , Trombocitose/veterinária , Anemia Macrocítica/diagnóstico , Anemia Macrocítica/patologia , Animais , Células da Medula Óssea/citologia , Células da Medula Óssea/patologia , Exame de Medula Óssea/veterinária , Doenças do Gato/patologia , Gatos , Complicações do Diabetes/terapia , Complicações do Diabetes/veterinária , Quimioterapia Combinada/veterinária , Leucemia Mieloide/diagnóstico , Leucemia Mieloide/patologia , Leucopenia/diagnóstico , Leucopenia/patologia , Masculino , Mycoplasma/genética , Mycoplasma/isolamento & purificação , Síndromes Mielodisplásicas/diagnóstico , Síndromes Mielodisplásicas/patologia , Síndromes Mielodisplásicas/veterinária , Doenças Mieloproliferativas-Mielodisplásicas/diagnóstico , Doenças Mieloproliferativas-Mielodisplásicas/patologia , Transtornos Mieloproliferativos/diagnóstico , Transtornos Mieloproliferativos/patologia , Transtornos Mieloproliferativos/veterinária , Trombocitose/diagnóstico , Trombocitose/patologia
3.
J Avian Med Surg ; 29(3): 224-30, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26378669

RESUMO

Two adult, male domestic turkeys were treated with implants of deslorelin acetate, a gonadotropin-releasing hormone agonist, to reduce intermale aggression and aggression directed toward the animal care team at a zoologic institution. The turkeys were manually restrained and either two 4.7-mg or two 9.4-mg implants were placed within the pectoral musculature on 3 occasions over the course of approximately 1.5 years. Plasma testosterone concentrations were measured by radioimmunoassay every 2 weeks for the first month after a new implant placement and then monthly thereafter. Testosterone concentrations remained low and aggressive behavior was decreased for a period of several months after implant placement. At necropsy of both birds, no adverse gross or histologic lesions were noted at the implantation sites in the pectoral musculature or within the gonadal tissue. Deslorelin acetate implants are a treatment modality to consider for mitigation of aggression in male domestic turkeys.


Assuntos
Agressão/efeitos dos fármacos , Comportamento Animal/efeitos dos fármacos , Inibidores Enzimáticos/farmacologia , Testosterona/sangue , Pamoato de Triptorrelina/análogos & derivados , Perus , Animais , Antineoplásicos Hormonais/administração & dosagem , Antineoplásicos Hormonais/farmacologia , Inibidores Enzimáticos/administração & dosagem , Leuprolida/administração & dosagem , Leuprolida/farmacologia , Pamoato de Triptorrelina/administração & dosagem , Pamoato de Triptorrelina/farmacologia , Perus/sangue
4.
J Zoo Wildl Med ; 45(3): 708-11, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25314849

RESUMO

A 7.5-yr-old female southern white rhinoceros (Ceratotherium simum simum) aborted spontaneously at approximately 13 mo gestation. The fetus exhibited malformations consistent with schistosomus reflexus syndrome, including spinal inversion and ventral midline abdominal defect with externalization of abdominal viscera. A computed tomography was performed and revealed severe scoliosis, a spiral rotation of the spine, multiple vertebral anomalies, hypoplasia of multiple bones of the skull, and mild prognathism. This is the first report of schistosomus reflexus-like syndrome in a nondomestic species, and the first report to characterize these skeletal changes by three-dimensional computed tomography.


Assuntos
Anormalidades Múltiplas/veterinária , Perissodáctilos/anormalidades , Anormalidades Múltiplas/patologia , Aborto Animal , Animais , Animais de Zoológico , Feminino , Feto
5.
Zoo Biol ; 33(6): 485-501, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25296396

RESUMO

Amphibian biology is intricate, and there are many inter-related factors that need to be understood before establishing successful Conservation Breeding Programs (CBPs). Nutritional needs of amphibians are highly integrated with disease and their husbandry needs, and the diversity of developmental stages, natural habitats, and feeding strategies result in many different recommendations for proper care and feeding. This review identifies several areas where there is substantial room for improvement in maintaining healthy ex situ amphibian populations specifically in the areas of obtaining and utilizing natural history data for both amphibians and their dietary items, achieving more appropriate environmental parameters, understanding stress and hormone production, and promoting better physical and population health. Using a scientific or research framework to answer questions about disease, nutrition, husbandry, genetics, and endocrinology of ex situ amphibians will improve specialists' understanding of the needs of these species. In general, there is a lack of baseline data and comparative information for most basic aspects of amphibian biology as well as standardized laboratory approaches. Instituting a formalized research approach in multiple scientific disciplines will be beneficial not only to the management of current ex situ populations, but also in moving forward with future conservation and reintroduction projects. This overview of gaps in knowledge concerning ex situ amphibian care should serve as a foundation for much needed future research in these areas.


Assuntos
Anfíbios/fisiologia , Criação de Animais Domésticos/métodos , Criação de Animais Domésticos/normas , Fenômenos Fisiológicos da Nutrição Animal , Animais de Zoológico , Conservação dos Recursos Naturais/métodos , Estágios do Ciclo de Vida/fisiologia , Anfíbios/metabolismo , Animais , Doenças Ósseas Metabólicas/prevenção & controle , Doenças Ósseas Metabólicas/veterinária , Cruzamento/métodos , Estresse Fisiológico/fisiologia , Deficiência de Vitamina A/prevenção & controle , Deficiência de Vitamina A/veterinária
6.
J Zoo Wildl Med ; 45(4): 892-5, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25632678

RESUMO

Recent issues surrounding captive amphibians are often nutritionally related problems, such as hypovitaminosis A. Although supplementation of frogs with vitamin A is a topic of investigation, the underlying issue is understanding vitamin A metabolism in amphibian species. To develop a range of "normal" vitamin A concentrations for captive amphibians, baseline vitamin A concentrations must be established in wild amphibian species. In this study, two species, Cuban tree frogs (Osteopilus septentrionalis; n = 59) and marine toads (Rhinella marina; n = 20) were collected from the wild as part of an invasive species control program at Zoo Miami, Miami, Florida. Serum, liver, and whole body samples were analyzed for vitamin A content. The Cuban tree frogs showed higher concentrations on average of vitamin A in serum (82.8 ppb), liver (248.3 IU/g), and whole body (5474.7 IU/kg) samples compared with marine toads (60.1 ppb; 105.3 IU/g; 940.7 IU/kg, respectively), but differences were not significant (P = 0.22). What can be considered "normal" values of vitamin A concentrations across different amphibian species requires further investigation. Although all amphibians collected in this study appeared healthy, a larger sample size of animals, with known health histories and diets, may provide stronger evidence of normal expectations.


Assuntos
Bufonidae/sangue , Fígado/química , Ranidae/sangue , Vitamina A/sangue , Vitamina A/química , Animais
7.
J Zoo Wildl Med ; 44(3): 700-13, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24063099

RESUMO

Although recognized as a potential complication after endotracheal intubation in birds, the complication rate of postintubation tracheal obstruction in this taxon is unknown. Twenty-three cases of postintubation obstruction in birds from two institutions are reported. Clinical signs were noted an average of 16.6 days postintubation and consisted primarily of indications of acute respiratory distress. Diagnosis was confirmed via tracheoscopy or radiology. Five birds died before treatment could be initiated. Medical treatment alone was successful in three birds that had mild changes consisting primarily of a luminal mucoid plug that could be manually removed without tracheal surgery but was unsuccessful in an additional six birds. Tracheal resection and anastamosis was successful in four birds and unsuccessful in five birds. Overall mortality was 70%. Postintubation tracheal obstruction in birds appears to be more common in zoo practice than is suggested by the literature, as a total of 1.8% (1.2-2.7%, 95% confidence interval) of intubations or 3.5% (2.3-5.3%, 95% confidence interval) of individual animals intubated in these institutions resulted in this complication. Multiple cases were found in Ciconiiformes (n = 4), Columbiformes (n = 4), Gruiformes (n = 4), Anseriformes (n = 3), Galliformes (n = 3), and Passeriformes (n = 2). No cases were found in Coraciiforms, Falconiforms, or Psittaciformes despite many (>40) recorded intubations. The specific cause of these lesions is unclear, but some type of tracheal mucosa trauma or irritation is suggested by histologic findings. Prevention may include selective intubation, use of a laryngeal mask airway in place of intubation, careful placement of an endotracheal tube, minimal movement of the head and neck after placement, humidification of anesthetic gases, and gentle positive-pressure ventilation.


Assuntos
Obstrução das Vias Respiratórias/veterinária , Doenças das Aves/etiologia , Aves , Intubação Intratraqueal/veterinária , Complicações Pós-Operatórias/veterinária , Obstrução das Vias Respiratórias/etiologia , Obstrução das Vias Respiratórias/mortalidade , Animais , Doenças das Aves/mortalidade , Doenças das Aves/patologia , Intubação Intratraqueal/efeitos adversos , Complicações Pós-Operatórias/mortalidade , Estudos Retrospectivos
8.
J Zoo Wildl Med ; 43(1): 125-30, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22448519

RESUMO

Three captive-born (5-day-old, 8-day-old, and 4-yr-old) Asian elephants (Elephas maximus) and one captive-born 22-yr-old African elephant (Loxodonta africana) from three private elephant facilities and one zoo in the United States presented with depression, anorexia, and tachycardia as well as gastrointestinal signs of disease including abdominal distention, decreased borborygmi, tenesmus, hematochezia, or diarrhea. All elephants showed some evidence of discomfort including agitation, vocalization, or postural changes. One animal had abnormal rectal findings. Nonmotile bowel loops were seen on transabdominal ultrasound in another case. Duration of signs ranged from 6 to 36 hr. All elephants received analgesics and were given oral or rectal fluids. Other treatments included warm-water enemas or walking. One elephant underwent exploratory celiotomy. Three animals died, and the elephant taken to surgery was euthanized prior to anesthetic recovery. At necropsy, all animals had severe, strangulating intestinal lesions.


Assuntos
Elefantes , Obstrução Intestinal/veterinária , Animais , Animais Recém-Nascidos , Evolução Fatal , Feminino , Obstrução Intestinal/patologia , Masculino
9.
J Zoo Wildl Med ; 42(2): 351-3, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22946421

RESUMO

A public aquarium with a 4-mo history of occasional fish mortalities submitted for necropsy an adult female largemouth bass (Micropterus salmoides) that died unexpectedly. Gross necropsy revealed that the pericardial cavity was markedly distended with partially coagulated blood. Examination of the heart revealed multiple nodular masses in the area of the atrium and two small perforations on the surface of one of the nodular masses. Histopathologic exam of the atrium revealed severe fibrinonecrotic endocarditis and transmural myocarditis with intralesional bacteria. A pure culture of Edwardsiella tarda was obtained from culture of posterior kidney and spleen. An area of stagnant water that may serve as the source of E. tarda was identified, and steps to rectify this problem were taken. Low-level supersaturation was also a significant stressor; the source of the supersaturation was not identified. To our knowledge, this is the first report of cardiac tamponade in a largemouth bass.


Assuntos
Bass , Tamponamento Cardíaco/veterinária , Infecções por Enterobacteriaceae/veterinária , Doenças dos Peixes/patologia , Animais , Tamponamento Cardíaco/etiologia , Tamponamento Cardíaco/patologia , Edwardsiella tarda/isolamento & purificação , Infecções por Enterobacteriaceae/complicações , Infecções por Enterobacteriaceae/microbiologia , Feminino , Doenças dos Peixes/etiologia , Doenças dos Peixes/microbiologia
10.
J Zoo Wildl Med ; 42(3): 468-72, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22950320

RESUMO

Two adult female bontebok (Damaliscus pygarus dorcas) were euthanized because of signs of pneumonia and weakness (case 1), and a nonresponsive lameness with draining fistula (case 2). Necropsy findings were similar in both cases and consisted of disseminated granulomatous lesions in the liver, kidneys, spleen, lungs, pleural surfaces, and multiple lymph nodes. Mycobacterium kansasii was isolated from both cases after multiple attempts on a variety of samples by two laboratories. The remaining four animals in the herd were tested for antibody responses using the Chembio ElephantTB STAT-PAK, DPP VetTB kits, and multi-antigen print immunoassay (MAPIA), for immune reaction using the intradermal tuberculin test, and by tracheal wash cultures, and thoracic radiographs. Banked serum samples collected in 2005 and obtained from the original institution, revealed 1/9 (11.11%) seropositive animals using the three immunoassays. Retesting the current herd in 2008 showed 2/6 (33.33%) seropositive animals by the three tests, with MAPIA demonstrating antibody reactivity to MPB83 and MPB70 proteins. Inconsistent intradermal tuberculin test results, cross-reactivity in serologic assays designed for tuberculosis detection, difficulty in obtaining definitive identification by culture, and inability to identify a source of infection created challenges in distinguishing the atypical mycobacteriosis due to M. kansasii from the initially suspected tuberculous infection in this herd. Owing to regulatory considerations, differences in host-to-host transmission, and source of infection between Mycobacterium tuberculosis complex and nontuberculous mycobacteria, correct diagnosis is crucial for management of these diseases in wildlife species.


Assuntos
Antílopes , Infecções por Mycobacterium não Tuberculosas/veterinária , Mycobacterium kansasii/classificação , Mycobacterium kansasii/isolamento & purificação , Mycobacterium tuberculosis/classificação , Animais , Técnicas Bacteriológicas , Feminino , Infecções por Mycobacterium não Tuberculosas/diagnóstico , Infecções por Mycobacterium não Tuberculosas/microbiologia
11.
J Zoo Wildl Med ; 41(3): 456-60, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20945643

RESUMO

Vitamin A is essential for a variety of functions, including cellular differentiation, morphogenesis, growth, vision, immune response, and reproduction. A captive population of African foam-nesting frogs (Chiromantis xerampelina) with a known history of vitamin A deficiency had higher than expected incidence of sudden death, bacterial osteomyelitis, and stunted growth. Due to the high prevalence and untreatable nature of the diseases in the population, euthanasia of the population was recommended. Before euthanasia, the population was entered into a study to compare oral dietary supplementation of vitamin A to topical treatment with water-miscible vitamin A palmitate (AQUASOL A Parenteral, Mayne Pharma Inc., Paramus, New Jersey 07652, U.S.A.). Eighty-four frogs, weighing 2-7 g, were divided into a control and three treatment groups of 21 frogs per group, with normalized weight distribution. The control group received standard daily nutrition of crickets dusted with a supplement containing 342,000 international units (IU) vitamin A/kg. The treatment groups consisted of oral supplementation with crickets dusted with a fortified supplement containing 822,510 IU vitamin A/kg; topical vitamin A palmitate 50 IU every other day; and topical vitamin A palmitate 50 IU once a week. After 30 days, all frogs were euthanized, and 12 frogs from each group were analyzed for whole-body vitamin A levels. The control and treatment groups 1, 2, and 3 had average whole-body vitamin A levels of 1371.4 IU/kg (SE 284.4), 908.7 IU/kg (SE 186.5), 6385.9 IU/kg (SE 675.9), and 3521.8 IU/kg (SE 575.1), respectively. These results suggest that oral supplementation using a product high in vitamin A may be ineffective at raising whole-body vitamin A levels above those achieved with standard nutrition. Topical administration of vitamin A on an every other day and once a week dosing schedule achieved levels 4.5- and 2.5-fold higher than standard nutrition, respectively.


Assuntos
Ranidae , Deficiência de Vitamina A/veterinária , Vitamina A/administração & dosagem , Vitamina A/farmacologia , Administração Oral , Administração Tópica , Ração Animal , Fenômenos Fisiológicos da Nutrição Animal , Animais , Animais de Zoológico , Peso Corporal/efeitos dos fármacos , Dieta/veterinária , Suplementos Nutricionais , Deficiência de Vitamina A/prevenção & controle
12.
Avian Pathol ; 38(5): 413-7, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19937528

RESUMO

Consensus polymerase chain reaction was used to identify a novel adenovirus from two psittacine birds: a plum-headed parakeet (Psittacula cyanocephala) with lethargy, weight loss, and marked leukocytosis; and an umbrella cockatoo (Cacatua alba) with lethargy, weight loss, and feather abnormalities. Phylogenetic and comparative sequence analysis suggested that this virus is a member of the genus Siadenovirus, and is here termed psittacine adenovirus 2. This extends the characterized adenoviruses of psittacine birds beyond Aviadenovirus to include the genus Siadenovirus. Identification and further study of adenoviral types and species will provide useful diagnostic, prognostic, and epidemiologic information for the clinician. Like other known members of the genus Siadenovirus, Psittacine adenovirus 2 is AT-rich over the region sequenced, and it is hypothesized that this may be associated with shorter host-virus evolutionary association.


Assuntos
Infecções por Adenoviridae/veterinária , Doenças das Aves/virologia , Cacatuas , Periquitos , Siadenovirus/fisiologia , Sequência Rica em At , Infecções por Adenoviridae/genética , Infecções por Adenoviridae/fisiopatologia , Infecções por Adenoviridae/virologia , Animais , Aviadenovirus/genética , Evolução Biológica , Doenças das Aves/genética , Doenças das Aves/fisiopatologia , DNA Viral , Plumas , Interações Hospedeiro-Patógeno/genética , Letargia , Linfocitose , Filogenia , Siadenovirus/isolamento & purificação , Redução de Peso
13.
J Zoo Wildl Med ; 40(1): 189-92, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19368260

RESUMO

An adult male, wild-caught fairy bluebird (Irena puella) was evaluated after diagnosis of hepatic mycobacterial disease in a bird sharing the same quarantine space. Initial results did not reveal leukocytosis or acid-fast organisms in a liver biopsy. However, Mycobacterium avium was found in the liver via polymerase chain reaction (PCR). After euthanasia, acid-fast stains remained negative in the liver, although PCR was positive and M. avium complex (identified by high-performance liquid chromatography) was isolated from the liver. PCR could offer a relatively sensitive and rapid diagnostic test in the investigation of mycobacterial disease in avian patients.


Assuntos
Mycobacterium avium/isolamento & purificação , Tuberculose Aviária/diagnóstico , Animais , Aves , Cromatografia Líquida de Alta Pressão/métodos , Cromatografia Líquida de Alta Pressão/veterinária , DNA Bacteriano/química , DNA Bacteriano/genética , Evolução Fatal , Masculino , Reação em Cadeia da Polimerase/métodos , Reação em Cadeia da Polimerase/veterinária
14.
J Wildl Dis ; 44(3): 537-52, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18689639

RESUMO

Feline leukemia virus (FeLV) was not detected in Florida pumas (Puma concolor coryi) in almost 20 yr of surveillance; however, the finding of two FeLV antigen-positive pumas during the 2002-2003 capture season led to an investigation of FeLV in the population. Between January 1990 and April 2007, the proportion of pumas testing FeLV antibody positive increased, with antibody-positive pumas concentrated in the northern portion of puma range. Five of 131 (4%) pumas sampled between July 2000 and April 2007 were viremic, with all cases clustered in Okaloacoochee Slough (OKS). Clinical signs and clinical pathology at capture were absent or included lymphadenopathy, moderate-to-severe anemia, and lymphopenia. All viremic pumas died; causes of death were septicemia (n=2), intraspecific aggression (n=2), and anemia/dehydration (n=1). Outcome after FeLV exposure in pumas was similar to that in domestic cats, with evidence of regressive, latent, and persistent infections. Management of the epizootic included vaccination, and as of April 2007, 52 free-ranging pumas had received one or more inoculations. Vaccinations were concentrated in OKS and in a band between OKS and the remainder of the puma population. There have been no new cases since July 2004; however, the potential for reintroduction of the virus remains.


Assuntos
Anticorpos Antivirais/sangue , Vírus da Leucemia Felina/imunologia , Puma/virologia , Infecções por Retroviridae/veterinária , Infecções Tumorais por Vírus/veterinária , Animais , Animais Selvagens , Feminino , Florida/epidemiologia , Vírus da Leucemia Felina/isolamento & purificação , Masculino , Infecções por Retroviridae/epidemiologia , Infecções por Retroviridae/mortalidade , Infecções por Retroviridae/patologia , Vigilância de Evento Sentinela/veterinária , Estudos Soroepidemiológicos , Infecções Tumorais por Vírus/epidemiologia , Infecções Tumorais por Vírus/mortalidade , Infecções Tumorais por Vírus/patologia , Vacinação/veterinária , Viremia/epidemiologia , Viremia/mortalidade , Viremia/patologia , Viremia/veterinária
15.
J Wildl Dis ; 44(2): 280-94, 2008 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-18436661

RESUMO

An investigation of adult alligator (Alligator mississippiensis) mortalities in Lake Griffin, central Florida, was conducted from 1998-2004. Alligator mortality was highest in the months of April and May and annual death count peaked in 2000. Bacterial pathogens, heavy metals, and pesticides were not linked with the mortalities. Blood chemistry did not point to any clinical diagnosis, although differences between impaired and normal animals were noted. Captured alligators with signs of neurologic impairment displayed unresponsive and uncoordinated behavior. Three of 21 impaired Lake Griffin alligators were found to have neural lesions characteristic of thiamine deficiency in the telencephalon, particularly the dorsal ventricular ridge. In some cases, lesions were found in the thalamus, and parts of the midbrain. Liver and muscle tissue concentrations of thiamine (vitamin B(1)) were lowest in impaired Lake Griffin alligators when compared to unimpaired alligators or to alligators from Lake Woodruff. The consumption of thiaminase-positive gizzard shad (Dorosoma cepedianum) is thought to have been the cause of the low tissue thiamine and resulting mortalities.


Assuntos
Jacarés e Crocodilos , Hidrolases/administração & dosagem , Hidrolases/metabolismo , Sistema Nervoso/patologia , Deficiência de Tiamina/veterinária , Jacarés e Crocodilos/metabolismo , Animais , Causas de Morte , Feminino , Florida , Masculino , Mortalidade , Exame Neurológico/veterinária , Estações do Ano , Tiamina/metabolismo , Tiamina/uso terapêutico , Deficiência de Tiamina/mortalidade , Deficiência de Tiamina/patologia
16.
J Am Vet Med Assoc ; 230(10): 1524-9, 2007 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-17504049

RESUMO

CASE DESCRIPTION: 4 captive adult Micronesian kingfishers (Halcyon cinnamomina cinnamomina) at 3 zoologic institutions were examined routinely or because of dyspnea or lethargy. CLINICAL FINDINGS: All birds had marked hepatomegaly. Two birds had dyspnea caused by compression of air sacs by the enlarged liver, and 1 bird had generalized weakness and lethargy. Three birds had distended coelomic cavities, and 3 birds were thin or had lost weight. There were no consistent abnormalities in blood analytes. Results of most ancillary diagnostic tests such as acid-fast staining of cloacal or fecal swab specimens and culture of feces for acid-fast bacteria were negative. Results of examination of hepatic biopsy specimens in 2 of 4 birds were suggestive of mycobacteriosis. TREATMENT AND OUTCOME: 3 birds died or were euthanized soon after diagnosis. One kingfisher was isolated and monitored for 4 months without treatment and died during anesthesia for disease monitoring. Postmortem histologic examination revealed histiocytic hepatitis and acid-fast bacteria in all 4 birds. Bacteriologic culture of liver specimens yielded Mycobacterium simiae complex in all 4 birds. CLINICAL RELEVANCE: Infection with M simiae complex should be considered in ill Micronesian kingfishers, and further monitoring is warranted to determine whether this is an emerging pathogen in this species.


Assuntos
Doenças das Aves/diagnóstico , Hepatopatias/veterinária , Infecções por Mycobacterium/veterinária , Animais , Animais Selvagens/microbiologia , Animais de Zoológico , Doenças das Aves/epidemiologia , Doenças das Aves/microbiologia , Aves , Surtos de Doenças/veterinária , Evolução Fatal , Feminino , Fígado/microbiologia , Fígado/patologia , Hepatopatias/diagnóstico , Hepatopatias/epidemiologia , Hepatopatias/microbiologia , Masculino , Mycobacterium/isolamento & purificação , Mycobacterium/patogenicidade , Infecções por Mycobacterium/diagnóstico , Infecções por Mycobacterium/epidemiologia , Infecções por Mycobacterium/microbiologia
17.
J Am Vet Med Assoc ; 228(8): 1240-2, 2006 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-16618230

RESUMO

CASE DESCRIPTION: 4 North American porcupines were evaluated because of diarrhea or neutropenia (or both) that developed after treatment with fenbendazole for intestinal parasites. CLINICAL FINDINGS: Complete blood cell count abnormalities included severe neutropenia in all affected porcupines and mild anemia in some of them. In 2 porcupines, postmortem findings included bone marrow hypoplasia and intestinal crypt cell necrosis. TREATMENT AND OUTCOME: Affected porcupines received supportive care including fluid supplementation and broad-spectrum antimicrobials. The 2 surviving animals recovered after 9 to 33 days of treatment. CONCLUSIONS AND CLINICAL RELEVANCE: Fenbendazole is an anthelminthic that may be used in an extralabel manner for the treatment of intestinal parasitism in wildlife species. The drug inhibits mitosis and can affect rapidly dividing cell lines, such as those in the bone marrow and intestinal crypt mucosa. Fenbendazole may not be an appropriate anthelminthic choice in North American porcupines.


Assuntos
Antinematódeos/efeitos adversos , Fenbendazol/efeitos adversos , Porcos-Espinhos , Animais , Antinematódeos/uso terapêutico , Contagem de Células Sanguíneas/veterinária , Diarreia/induzido quimicamente , Diarreia/veterinária , Evolução Fatal , Feminino , Fenbendazol/uso terapêutico , Enteropatias Parasitárias/tratamento farmacológico , Enteropatias Parasitárias/veterinária , Masculino
18.
J Parasitol ; 91(1): 199-201, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15856903

RESUMO

A 4-mo-old male Japanese white-naped crane (Grus vipio) kept in an outdoor exhibit at the Everland Zoological Gardens in Korea became depressed and developed anorexia, weight loss, and diarrhea. Death of this bird was associated with an overwhelming systemic infection by an intracellular coccidian parasite, which resulted in necrosis and granulomatous inflammation in a number of major organs, including the intestine, liver, spleen, and kidney. Coccidian parasite-laden macrophages were commonly found in the blood vessels of these organs. Using electron microscopy and polymerase chain reaction assays, the parasite was identified as Eimeria sp. The bird was also infected with Cryptosporidium sp., which suggests an immunosuppressed state, although the cause of such suppression was not identified. Our findings suggest that an initial Eimeria sp. intestinal infection spread to other organs through the blood vessels, with the immunosuppressed state possibly contributing to a rapid hematogenous transmission. To our knowledge, this is the first report of disseminated visceral coccidiosis caused by Eimeria sp. in a captive Japanese white-naped crane.


Assuntos
Doenças das Aves/parasitologia , Coccidiose/veterinária , Criptosporidiose/veterinária , Eimeria/isolamento & purificação , Animais , Doenças das Aves/diagnóstico , Doenças das Aves/imunologia , Aves , Cloaca/parasitologia , Coccidiose/complicações , Coccidiose/diagnóstico , Sequência Consenso , Criptosporidiose/complicações , Criptosporidiose/diagnóstico , Cryptosporidium/isolamento & purificação , Cryptosporidium/ultraestrutura , DNA de Protozoário/química , DNA de Protozoário/isolamento & purificação , Eimeria/genética , Evolução Fatal , Tolerância Imunológica/imunologia , Intestinos/parasitologia , Intestinos/patologia , Rim/parasitologia , Rim/patologia , Fígado/parasitologia , Fígado/patologia , Pulmão/parasitologia , Pulmão/patologia , Masculino , Microscopia Eletrônica/veterinária , Reação em Cadeia da Polimerase/veterinária , Proventrículo/parasitologia , Proventrículo/patologia
19.
Vet Microbiol ; 105(2): 83-92, 2005 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-15627519

RESUMO

Stomatitis is a common problem in lizards, and the etiologies of stomatitis in lizards are not well understood. Four green tree monitor lizards (Varanus prasinus) from two different collections were evaluated because of proliferative stomatitis. Degenerate PCR primers targeting a conserved region of herpesvirus DNA-dependent DNA polymerase were used to amplify and sequence a product from gingival tissue of three of four lizards (cases 1, 3, and 4). DNA in situ hybridization of tissues from three lizards was positive for herpesvirus in the oral mucosa of all three lizards tested (cases 1-3) and the brain of two lizards (cases 1 and 3). Comparative sequence analysis suggests that this virus is a novel member of the subfamily alpha-herpesvirinae, and is here termed varanid herpesvirus 1.


Assuntos
Infecções por Herpesviridae/veterinária , Herpesviridae/crescimento & desenvolvimento , Lagartos/virologia , Estomatite Herpética/veterinária , Animais , Sequência de Bases , DNA Viral/química , DNA Viral/genética , Feminino , Herpesviridae/genética , Infecções por Herpesviridae/patologia , Infecções por Herpesviridae/virologia , Dados de Sequência Molecular , Mucosa Bucal/virologia , Hibridização de Ácido Nucleico , Filogenia , Reação em Cadeia da Polimerase/veterinária , Estomatite Herpética/patologia , Estomatite Herpética/virologia
20.
J Zoo Wildl Med ; 36(3): 509-11, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-17312773

RESUMO

A 10-yr-old male gorilla (Gorilla gorilla gorilla) with a history of conspecific bite wounds was evaluated for acute onset of depression, anorexia, and right hemiparesis. The animal was immobilized for diagnostic examination and treatment for suspected toxic shock from a necrotizing, emphysematous wound infection, but was euthanized due to complications during recovery. Gross and histopathologic examination revealed acute necrotizing myositis, fasciitis, cellulitis, and emphysema in the affected wound area, with large numbers of large Gram-positive rods among necrotic muscle fibers. Severe pulmonary edema with airways containing fibrin, acute hemorrhage in multiple body sites, thrombosis in blood vessels in the skeletal muscle, liver, and lung, and lymph node hyperplasia with lymphoid necrosis and hemorrhage. Immunohistochemical fluorescent antibody staining of muscle from the wound site was positive for


Assuntos
Doenças dos Símios Antropoides/diagnóstico , Infecções por Clostridium/veterinária , Clostridium septicum/isolamento & purificação , Gorilla gorilla , Miosite/veterinária , Infecção dos Ferimentos/veterinária , Animais , Doenças dos Símios Antropoides/microbiologia , Mordeduras e Picadas , Infecções por Clostridium/complicações , Infecções por Clostridium/diagnóstico , Clostridium septicum/imunologia , Evolução Fatal , Masculino , Miosite/diagnóstico , Miosite/microbiologia , Infecção dos Ferimentos/complicações , Infecção dos Ferimentos/diagnóstico
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...