RESUMO
In a 38-year-old patient 17 years previously silicone prostheses of both breasts were implanted. Three years after operation spontaneous abortions developed, later repeated venous and arterial thromboses. Laboratory examinations revealed antibodies against cardiolipin and the diagnosis of anticardiolipin syndrome was established. The authors discuss the relationship between the performed operation and the present disease.
Assuntos
Síndrome Antifosfolipídica/etiologia , Autoanticorpos/análise , Cardiolipinas/imunologia , Mamoplastia/efeitos adversos , Próteses e Implantes/efeitos adversos , Adulto , Feminino , Humanos , SiliconesRESUMO
A 38-year-old female patient had bilateral silicone-made prosthesis implantation performed 17 years ago. Three years after surgery, she had a series of spontaneous miscarriages, later she developed recurrent venous and arterial thromboses. Laboratory tests detected antibodies against cardiolipin and the diagnosis of cardiolipin syndrome was established. The authors discuss the possible association between surgery and the patient's current disease.
Assuntos
Autoanticorpos/análise , Mama/cirurgia , Cardiolipinas/imunologia , Complicações Pós-Operatórias/diagnóstico , Próteses e Implantes , Silicones , Trombose/imunologia , Aborto Habitual/imunologia , Adulto , Testes de Coagulação Sanguínea , Feminino , Seguimentos , Humanos , Complicações Pós-Operatórias/sangue , Síndrome Pós-Flebítica/imunologia , GravidezAssuntos
Catepsina D/metabolismo , Dipeptidil Peptidases e Tripeptidil Peptidases/metabolismo , Hidrocortisona/análogos & derivados , Osteoartrite/enzimologia , Fenilbutazona/análogos & derivados , Fenilbutazona/uso terapêutico , Animais , Osso e Ossos/enzimologia , Cartilagem Articular/enzimologia , Catepsina C , Feminino , Hidrocortisona/uso terapêutico , Osteoartrite/tratamento farmacológico , CoelhosAssuntos
Osso e Ossos/enzimologia , Cartilagem Articular/enzimologia , Articulação do Joelho , Metaloendopeptidases , Osteoartrite/enzimologia , Animais , Catepsina C , Catepsina D/metabolismo , Dipeptidil Peptidases e Tripeptidil Peptidases/metabolismo , Endopeptidases/metabolismo , Feminino , Pirofosfatases/metabolismo , CoelhosRESUMO
The authors characterize the position which developed in the sphere of rheumatic diseases, in particular inflammatory ones, after in these diseases the association with HLA antigens was revealed; most important is still the association of HLA B 27 with ankylosing spondylitis (Bekhterev's disease) which stimulated a new line of research and helped to detect the projection of antigen into all so-called rheumatic diseases which have in addition to affected peripheral joints inflammatory change of the SI synchrondrosis and segmentary signs of ankylosing spondylitis. The authors examined patients with psoriatic arthropathy and pure dermatological psoriasis but found only association with B 17 and B 13. In ankylosing hyperotosis (Forestier) they prove, based on the findings in 36 patients that in controversial cases the absence of B 27 may be important. They report also on their finding of an enhanced association of A 10 and B 14 in a group of 48 patients with seropositive rheumatoid arthritis.
Assuntos
Antígenos HLA/análise , Doenças Reumáticas/imunologia , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/imunologia , Diagnóstico Diferencial , Humanos , Polimialgia Reumática/imunologia , Prognóstico , Psoríase/diagnóstico , Psoríase/imunologia , Doenças Reumáticas/diagnóstico , Espondilite Anquilosante/diagnóstico , Espondilite Anquilosante/imunologiaRESUMO
In a series of 58 patients with psoriasis and skin involvement in the absence of any symptoms of an associated joint or bone disease, 49 individuals had definite signs of an arthritis of the sacro-iliac joints, while only slight changes were present in the others. The authors reached the conclusions that arthritis of the sacro-iliac joints occurs in all patients with psoriasis, without any exceptions; and thus not only in those who have simultaneous symptoms of bone or joint disease, which are well known in psoriasis, but equally in those in whom the clinical symptoms are missing.
Assuntos
Artrite/complicações , Psoríase/complicações , Articulação Sacroilíaca , Adulto , Artrite/diagnóstico por imagem , Feminino , Antígenos HLA/análise , Humanos , Masculino , Pessoa de Meia-Idade , Psoríase/diagnóstico por imagem , Psoríase/imunologia , Radiografia , Articulação Sacroilíaca/diagnóstico por imagemRESUMO
Roentgenographic studies of the sacroiliac joints were carried out in 117 psoriatic patients with associated symptoms of joint and/or bone involvement and in eleven psoriatic patients without signs of bone or joint disease. In all patients arthritis of the sacro-iliac joints with varying degree of severity was demonstrated. The sacro-iliac joint space remained open in patients without associated rheumatoid arthritis or ankylosing spondylarthritis. It was shown that the described method in the assessment of the sacro-iliac joints is fully justified.