RESUMO
Hibernoma is a rare, benign soft tissue tumor described in <200 case reports/case series. It is slow-growing, painless, and commonly mistaken for lipoma or liposarcoma. Histopathological diagnosis is must for confirmation. Total excision is the treatment of choice. We present a rare case of hibernoma of thigh, which was initially misdiagnosed as atypical lipomatous tumor/well-differentiated liposarcoma on imaging, which turned out to be a hibernoma on histopathological examination.
Assuntos
Tecido Adiposo Marrom , Erros de Diagnóstico , Lipoma/diagnóstico por imagem , Adulto , Biópsia , Diagnóstico Diferencial , Feminino , Humanos , Lipoma/cirurgia , Lipossarcoma/diagnóstico , Imageamento por Ressonância Magnética , Coxa da Perna/patologia , Resultado do TratamentoRESUMO
We present the autopsy findings and differential diagnosis of a 37-year-old immunocompetent male patient who presented primarily with extensive cerebral vein thrombosis and was found to have a rare association with JAK2V617F mutation positivity.
Assuntos
Encéfalo/patologia , Linfoma de Burkitt , Trombose Intracraniana/diagnóstico , Janus Quinase 2/genética , Trombose Venosa/diagnóstico , Adulto , Encéfalo/diagnóstico por imagem , Linfoma de Burkitt/diagnóstico , Linfoma de Burkitt/genética , Linfoma de Burkitt/mortalidade , Linfoma de Burkitt/patologia , Humanos , Trombose Intracraniana/diagnóstico por imagem , Imageamento por Ressonância Magnética , Masculino , Trombose Venosa/diagnóstico por imagemRESUMO
Diagnosis of Strongyloides stercoralis hyperinfection can be a challenge. The key to a timely diagnosis is to have a high index of suspicion. We present a rare case of a 36-year-old human immunodeficiency virus negative male patient, who was on multidrug therapy for lepromatous leprosy and was treated for type 2 lepra reactions with steroids in the past. The patient presented with vomiting and pain abdomen, persistent hyponatremia, and terminal hypoglycemia. He had features of malnutrition and had a rapid downhill course following admission. A diagnosis of S. stercoralis hyperinfection with sepsis and multiorgan failure, adrenal hemorrhage, and syndrome of inappropriate antidiuretic hormone secretion was established on a postmortem examination.
Assuntos
Sepse/etiologia , Sepse/patologia , Strongyloides stercoralis/isolamento & purificação , Estrongiloidíase/diagnóstico , Estrongiloidíase/patologia , Dor Abdominal/etiologia , Adulto , Animais , Humanos , Hipoglicemia/etiologia , Hiponatremia/etiologia , Hanseníase Virchowiana/complicações , Hanseníase Virchowiana/tratamento farmacológico , Masculino , Estrongiloidíase/complicações , Vômito/etiologia , Redução de PesoRESUMO
Acanthamoeba species are free-living amoebae that are the causative agents of chronic granulomatous meningoencephalitis, amoebic keratitis, pulmonary lesions, cutaneous lesions and sinusitis. Immunocompromised individuals are particularly susceptible to infections with Acanthamoeba, which can be disseminated at times. We herewith report the autopsy findings of disseminated Acanthamoeba infection in a 36-year-old female, a renal transplant recipient on immunosupressants for last four years. Central nervous system showed Acanthamoeba associated chronic granulomatous meningoencephalitis, with predominant perivascular infiltrate of amoebic cysts, trophozoites and inflammatory cells. Both lungs and pancreas also showed infiltration with Acanthamoeba.
