RESUMO
PURPOSE: The estimated prevalence of cryptorchidism in young males is close to 2%. In oncological PET/CT studies, it might be difficult to recognize false-positive ¹8FDG uptake due to an ectopic testis. MATERIALS AND METHODS: In this pilot study, we report on three patients with lymphoma referred for assessment of response to treatment and in whom cryptorchidism was not known at the time of ¹8FDG-PET/CT imaging. RESULTS: In each of these patients, moderate ¹8FDG uptake corresponding to an ovoid mass in the inguinal canal was (or could has been) misinterpreted as a lymphoma-involved inguinal lymph node. Clues to avoid misinterpretation are discussed. CONCLUSION: Moderate ¹8FDG uptake in ectopic testes represents a potential source of false-positive at initial staging or evaluation of therapeutic response of lymphomas and other malignancies that needs to be recognized.
Assuntos
Criptorquidismo/diagnóstico por imagem , Criptorquidismo/diagnóstico , Fluordesoxiglucose F18/administração & dosagem , Linfoma/diagnóstico por imagem , Linfoma/patologia , Adulto , Criptorquidismo/patologia , Humanos , Linfonodos/diagnóstico por imagem , Linfonodos/patologia , Masculino , Imagem Multimodal/métodos , Estadiamento de Neoplasias , Projetos Piloto , Tomografia por Emissão de Pósitrons/métodos , Prognóstico , Compostos Radiofarmacêuticos/administração & dosagem , Tomografia Computadorizada por Raios X/métodos , Adulto JovemAssuntos
Candidíase/diagnóstico por imagem , Fluordesoxiglucose F18 , Hepatopatias/diagnóstico por imagem , Esplenopatias/diagnóstico por imagem , Antifúngicos/uso terapêutico , Candidíase/complicações , Candidíase/tratamento farmacológico , Fluconazol/uso terapêutico , Humanos , Leucemia Mieloide Aguda/complicações , Leucemia Mieloide Aguda/tratamento farmacológico , Hepatopatias/microbiologia , Masculino , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Esplenopatias/microbiologia , Tomografia Computadorizada por Raios X , Adulto JovemRESUMO
OBJECTIVES: Esophageal cancer outcome greatly depends on the pathological stage. Our objectives were to assess prognosis on the basis of the initial fluorodeoxyglucose (FDG)-PET scan, focusing on the correlation between overall survival and FDG uptake in the primary, as well as the presence of FDG-positive lymph nodes or distant metastases. METHODS: Fifty-two esophageal cancer patients undergoing FDG-PET as part of initial routine staging procedure before treatment were included. The maximum standardized uptake value (SUV max) was determined in each primary lesion and the number of abnormalities including primary, lymph nodes, or distant metastases was recorded. Correlation with overall survival was performed using Kaplan-Meier method and Cox regression analysis was used to assess the prognostic value of PET parameters. RESULTS: Half of the patients were planned for initial curative surgery (52%). Using univariate survival analysis, either surgery, SUV max >9, two or more PET abnormalities or the presence of FDG-positive nodes were significant overall survival prognostic predictors. After multivariate analysis, only SUV max >9 and FDG-positive lymph nodes were found as independent predictors of poor outcome. CONCLUSION: In this prospective study, FDG-PET was found to provide prognostic information supporting a new indication for initial FDG-PET examination in esophageal cancer.
