Rare complications of chronic cholangitis: Pseudoaneurysm of the hepatic artery causing serious gastrointestinal bleeding.

Gastrointestinal bleeding due to hemobilia is a rare condition but can be very serious, even life-threatening. The main causes of biliary bleeding are invasive procedures in treatment, trauma, or malignant diseases. Chronic obstruction of the biliary tract can cause inflammation, erosion, and leakage of adjacent vascular structures and lead to pseudoaneurysm or hemorrhage, but this is very rare. In this article, we present a clinical case of upper gastrointestinal bleeding due to a pseudoaneurysm of the hepatic artery believed to have formed due to chronic cholangitis. An 81-year-old female patient with a medical history of chronic cholangitis was admitted to the hospital with recurrent inflammation accompanied by progressive upper gastrointestinal bleeding, potentially life-threatening. Ultrasound images and blood tests confirmed that the patient had anemia and cholangitis caused by stones. Gastrointestinal endoscopy showed bleeding suspected to be from the biliary tract. Hepatobiliary computed tomography confirmed that the common hepatic artery pseudoaneurysm located at the upper end of the common bile duct had active bleeding.

A rare case of bilateral primary renal Burkitt lymphoma presenting with acute renal failure.

Acute renal failure due to primary renal Burkitt lymphoma in children is extremely rare. We report a case with acute secondary renal failure in a 4-year-old boy who presented with abdominal pain, anorexia, and vomiting. Abdominal computed tomography scans showed bilateral nephromegaly with multiple hypoenhancing regions. Renal biopsy confirmed Burkitt lymphoma. There was no lymphadenopathy or evidence of other solid organ involvement. The patient was responsive to treatment using the EPOCH-R protocol (etoposide, prednisone, vincristine, cyclophosphamide , doxorubicin, and rituximab). Here, we describe the clinical and imaging features associated with this rare entity.

A case report of cerebrospinal fluid leak secondary to inner ear malformation.

Spontaneous cerebrospinal fluid (CSF) rhinorrhea is rare and may develop secondary to inner ear malformation. A possible diagnosis of CSF leak should be considered in any pediatric patient who presents with hearing impairment, rhinorrhea, or otorrhea. Temporal bone computed tomography should be performed in children with hearing impairments. We describe a case of congenital inner ear anomaly in a 12-month-old girl who presented with intermittent rhinorrhea after birth and detected hearing problems when she was 6 months. After diagnosis, the CSF leak was surgically repaired without complications.

Electrochemical Sensor Based on Reduced Graphene Oxide/Double-Walled Carbon Nanotubes/Octahedral Fe3O4/Chitosan Composite for Glyphosate Detection.

In this work, reduced graphene oxide/double-walled carbon nanotubes/octahedral-Fe3O4/chitosan composite material modified screen-printed gold electrodes (rGO/DWCNTs/Oct-Fe3O4/Cs/SPAuE) under inhibition of urease enzyme was developed for the determination of glyphosate (GLY). The electrochemical behaviors of GLY on these electrodes were evaluated by square wave voltammetry (SWV). With the electroactive surface area is 1.7 times higher than that of bare SPAuE, the rGO/DWCNTs/Oct-Fe3O4/Cs/SPAuE for detection of GLY shows a low detection limit (LOD) of ~ 0.08 ppb in a large concentration range of 0.1-1000 ppb. Moreover, it is also successfully applied to the determination of GLY in river water samples with recoveries and relative standard deviations (RSDs) from 98.7% to 106.9% and from 0.79% to 0.87%, respectively. The developed composite will probably provide an universal electrochemical sensing platform that is very promising for environmental monitoring.