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1.
J Integr Neurosci ; 17(2): 133-148, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-28968248

RESUMO

Understanding and analyzing the dynamic interactions among millions of spatially distributed and functionally connected regions in the human brain constituting a massively parallel communication system is one of the major challenges in computational neuroscience. Many studies in the recent past have employed graph theory to efficiently model, quantitatively analyze, and understand the brain's electrical activity. Since, the human brain is believed to broadcast information with reduced material and metabolic costs, identifying various brain regions in the shortest pathways of information dissemination becomes essential to understand the intricacies of brain function. This paper proposes a graph theoretic approach using the concept of shortest communication paths between various brain regions (electrode sites) to identify the significant communication pathways of information exchange between various nodes in the functional brain networks constructed from multi-channel electroencephalograph data. A special weighted network called the Shortest Path Network is constructed from a functional brain network where the edge weight is computed as the sum of frequency of occurrence of that edge in all possible shortest paths between every pair of electrodes. The weighted Shortest Path Networks thus constructed portray information on the number of times the edges are used in information propagation during different cognitive states. This network is further analyzed by computing the influential communication paths to characterize the information dissemination among brain regions during different cognitive load conditions. The experimental results presented demonstrate the efficacy of this novel graph theoretic approach in identifying, quantifying, and comparing the significant shortest pathways of information exchange during mild and heavy cognitive load conditions. Analysis also suggests that future research should consider the biological inferences of the ability of the human brain to use reduced material and metabolic cost during the instantaneous transmission of information.


Assuntos
Encéfalo/fisiologia , Cognição/fisiologia , Eletroencefalografia , Processamento de Sinais Assistido por Computador , Humanos , Modelos Teóricos
2.
J Integr Neurosci ; 15(2): 223-45, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27401999

RESUMO

The complex nature of neuronal interactions of the human brain has posed many challenges to the research community. To explore the underlying mechanisms of neuronal activity of cohesive brain regions during different cognitive activities, many innovative mathematical and computational models are required. This paper presents a novel Common Functional Pattern Mining approach to demonstrate the similar patterns of interactions due to common behavior of certain brain regions. The electrode sites of EEG-based functional brain network are modeled as a set of transactions and node-based complex network measures as itemsets. These itemsets are transformed into a graph data structure called Functional Pattern Graph. By mining this Functional Pattern Graph, the common functional patterns due to specific brain functioning can be identified. The empirical analyses show the efficiency of the proposed approach in identifying the extent to which the electrode sites (transactions) are similar during various cognitive load states.


Assuntos
Mapeamento Encefálico/métodos , Encéfalo/fisiologia , Cognição/fisiologia , Eletroencefalografia/métodos , Reconhecimento Automatizado de Padrão/métodos , Atenção/fisiologia , Percepção Auditiva/fisiologia , Condução de Veículo/psicologia , Análise por Conglomerados , Mineração de Dados/métodos , Eletroencefalografia/instrumentação , Humanos , Masculino , Vias Neurais/fisiologia , Testes Neuropsicológicos
3.
J Food Sci Technol ; 49(3): 373-7, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23729859

RESUMO

The effects of different cooking methods (boiling, baking, frying and grilling) on proximate and mineral composition of snakehead fish were investigated. The mean content of moisture, protein, fat and ash of raw fish was found to be 77.2 ± 2.39, 13.9 ± 2.89, 5.9 ± 0.45 and 0.77 ± 0.12% respectively. The changes in the amount of protein and fat were found to be significantly higher in frying and grilling fish. The ash content increased significantly whereas that of the minerals (Na, K, Ca, Mg, Fe, Zn and Mn) was not affected in all cooking methods. Increased in Cu contents and decreased in P contents were observed in all cooking methods except grilling. In the present study, the grilling method of cooking is found to be the best for healthy eating.

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