1.
Org Biomol Chem
; 1(2): 373-80, 2003 Jan 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12929433
RESUMO
beta-Keto esters and beta-keto amides can be efficiently alkylated on reaction with enol ethers and manganese(III) acetate in the presence of copper(II) acetate. These intermolecular radical addition reactions can be used to construct quaternary carbon centres in excellent yield and this method has been utilised in a diastereoselective approach to substituted pyrrolidinones.