[Biological properties of 4-amino-5 alkyl-sulfone substituted orthoanisamides]. / Propriétés biologiques d'orthoanisamides substitués à fonction-4 amino-5 alkyl-sulfone.

The 4-amino 5-alkyl-sulfone substituted orthoanisamides can be distinguished from their non-aminated homologues (sultopride) or sulfamoyl homologues (sulpride) mainly by the intensity of their anti-emetic effects with regard to apomorphine and their mode of action, either on hippocampic rhythms or on locomotor rhythms in the Cat.

[Endocrinological effects of substituted orthoveratramides]. / Recherches sur les effets endocriniens des orthovératramides substitués.

The substituted orthoveratramides, derived from the orthopramides by the addition of a second methoxy radical at position 3 in the benzene ring, possess strong endocrinological effects. In particular the N[(allyl-1 pyrrolidinyl-2) methyl] dimethoxy-2-3 sulfamoyl-5 benzamide blocks oestrus in the Rat at doses considerably lower than sultopride and inhibits so-called "castration cell" formation in the pituitary.