The impact of functional combined anteversion on hip range of motion: a new optimal zone to reduce risk of impingement in total hip arthroplasty.

AIMS: Pelvic tilt (PT) can significantly change the functional orientation of the acetabular component and may differ markedly between patients undergoing total hip arthroplasty (THA). Patients with stiff spines who have little change in PT are considered at high risk for instability following THA. Femoral component position also contributes to the limits of impingement-free range of motion (ROM), but has been less studied. Little is known about the impact of combined anteversion on risk of impingement with changing pelvic position. METHODS: We used a virtual hip ROM (vROM) tool to investigate whether there is an ideal functional combined anteversion for reduced risk of hip impingement. We collected PT information from functional lateral radiographs (standing and sitting) and a supine CT scan, which was then input into the vROM tool. We developed a novel vROM scoring system, considering both seated flexion and standing extension manoeuvres, to quantify whether hips had limited ROM and then correlated the vROM score to component position. RESULTS: The vast majority of THA planned with standing combined anteversion between 30° to 50° and sitting combined anteversion between 45° to 65° had a vROM score > 99%, while the majority of vROM scores less than 99% were outside of this zone. The range of PT in supine, standing, and sitting positions varied widely between patients. Patients who had little change in PT from standing to sitting positions had decreased hip vROM. CONCLUSION: It has been shown previously that an individual's unique spinopelvic alignment influences functional cup anteversion. But functional combined anteversion, which also considers stem position, should be used to identify an ideal THA position for impingement-free ROM. We found a functional combined anteversion zone for THA that may be used moving forward to place total hip components. Cite this article: Bone Jt Open 2021;2(10):834-841.

Range of Motion to Impingement Curves Create a New Patient-Specific Impingement-Free Zone for Acetabular Cup Placement.

INTRODUCTION: The acetabular "safe zone" has recently been questioned as a reliable reference for predicting total hip arthroplasty impingement and instability as many dislocations occur within the described parameters. Recently, an improved understanding of spino-pelvic mechanics has provided surgeons useful information to both identify those at a higher risk of dislocation and, in some cases, allows altering component positioning to accommodate the patient's individual "functional" range of motion. The purpose of this study was to create a new patient-specific impingement-free zone by considering range of motion (ROM) to prosthetic impingement for both high flexion and extension poses, thus demarcating a zone that avoids both anterior and posterior impingement, thereby creating an objective approach to identifying a patient's ideal functional safe zone. MATERIALS AND METHODS: A validated hip ROM three-dimensional simulator was utilized to create ROM-to-impingement curves for both high flexion as well as pivot and turn poses. The user imported a computerized tomography (CT) with a supine pelvic tilt (PT) value of zero and implant models (tapered wedge stem, 132° neck angle, 15° stem version, 36mm femoral head). Femur-to-pelvis relative motions were determined for three upright seated poses (femur flexed at 90° and 40° internal rotation, with 0°, 10°, and 20° posterior PT), one chair rise pose (femur flexed at 90° and 0° internal rotation, with the pelvis flexed anteriorly until the pelvis made contact with the femur), and three standing pivot and turn poses (femur set at 5° extension, and 35° external rotation, with 5° posterior PT, 0°, and 5° anterior PT). ROM-to-impingement curves for cup inclination versus anteversion were graphed and compared against the Lewinnek safe zone. RESULTS: The ROM-to-impingement curves provide an objective assessment of potential impingement sites as they relate to femoral rotation and pelvic tilt. The area between the stand and sit curves is the impingement-free area. A sitting erect pose with a simulated stiff spine (0° PT) yielded less impingement-free combinations of cup inclination and version than poses with greater than 0° posterior pelvic tilt. CONCLUSION: The results demonstrate that the acetabular target zone has a relatively small margin for error between the sitting and standing ROM curves to impingement. Importantly, anterior and posterior pelvic tilt can markedly increase the risk of impingement, potentially leading to posterior or anterior dislocations, respectively. This study highlights the importance of correctly identifying the patient-specific functional range of motion to execute optimal component positioning.

Strategy of endovascular versus open repair for patients with clinical diagnosis of ruptured abdominal aortic aneurysm: the IMPROVE RCT.

BACKGROUND: Ruptured abdominal aortic aneurysm (AAA) is a common vascular emergency. The mortality from emergency endovascular repair may be much lower than the 40-50% reported for open surgery. OBJECTIVE: To assess whether or not a strategy of endovascular repair compared with open repair reduces 30-day and mid-term mortality (including costs and cost-effectiveness) among patients with a suspected ruptured AAA. DESIGN: Randomised controlled trial, with computer-generated telephone randomisation of participants in a 1 : 1 ratio, using variable block size, stratified by centre and without blinding. SETTING: Vascular centres in the UK (n = 29) and Canada (n = 1) between 2009 and 2013. PARTICIPANTS: A total of 613 eligible participants (480 men) with a ruptured aneurysm, clinically diagnosed at the trial centre. INTERVENTIONS: A total of 316 participants were randomised to the endovascular strategy group (immediate computerised tomography followed by endovascular repair if anatomically suitable or, if not suitable, open repair) and 297 were randomised to the open repair group (computerised tomography optional). MAIN OUTCOME MEASURES: The primary outcome measure was 30-day mortality, with 30-day reinterventions, costs and disposal as early secondary outcome measures. Later outcome measures included 1- and 3-year mortality, reinterventions, quality of life (QoL) and cost-effectiveness. RESULTS: The 30-day mortality was 35.4% in the endovascular strategy group and 37.4% in the open repair group [odds ratio (OR) 0.92, 95% confidence interval (CI) 0.66 to 1.28; p = 0.62, and, after adjustment for age, sex and Hardman index, OR 0.94, 95% CI 0.67 to 1.33]. The endovascular strategy appeared to be more effective in women than in men (interaction test p = 0.02). More discharges in the endovascular strategy group (94%) than in the open repair group (77%) were directly to home (p < 0.001). Average 30-day costs were similar between groups, with the mean difference in costs being -£1186 (95% CI -£2997 to £625), favouring the endovascular strategy group. After 1 year, survival and reintervention rates were similar in the two groups, QoL (at both 3 and 12 months) was higher in the endovascular strategy group and the mean cost difference was -£2329 (95% CI -£5489 to £922). At 3 years, mortality was 48% and 56% in the endovascular strategy group and open repair group, respectively (OR 0.73, 95% CI 0.53 to 1.00; p = 0.053), with a stronger benefit for the endovascular strategy in the subgroup of 502 participants in whom repair was started for a proven rupture (OR 0.62, 95% CI 0.43 to 0.89; p = 0.009), whereas aneurysm-related reintervention rates were non-significantly higher in this group. At 3 years, considering all participants, there was a mean difference of 0.174 quality-adjusted life-years (QALYs) (95% CI 0.002 to 0.353 QALYs) and, among the endovascular strategy group, a cost difference of -£2605 (95% CI -£5966 to £702), leading to 88% of estimates in the cost-effectiveness plane being in the quadrant showing the endovascular strategy to be 'dominant'. LIMITATIONS: Because of the pragmatic design of this trial, 33 participants in the endovascular strategy group and 26 in the open repair group breached randomisation allocation. CONCLUSIONS: The endovascular strategy was not associated with a significant reduction in either 30-day mortality or cost but was associated with faster participant recovery. By 3 years, the endovascular strategy showed a survival and QALY gain and was highly likely to be cost-effective. Future research could include improving resuscitation for older persons with circulatory collapse, the impact of local anaesthesia and emergency consent procedures. TRIAL REGISTRATION: Current Controlled Trials ISRCTN48334791 and NCT00746122. FUNDING: This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 22, No. 31. See the NIHR Journals Library website for further project information.

Etiology and severity of impingement injuries of the acetabular labrum: what is the role of femoral morphology?

Injuries to the acetabular labrum have been seen in association with femoroacetabular impingement, but recent studies have reported labral pathology in patients with normal hip morphology. The hypothesis of the current study was that labral lesions could occur without femoroacetabular impingement but that labral pathology would occur more commonly and more severely in hip joints that exhibit reduced head-neck offset. The presence, location, and severity of labral injury were recorded in 22 cadaveric specimens. Computed tomography was used to define the anatomic parameters of proximal femoral morphology. Three-dimensional modeling was used to simulate hip positions that typically cause labral impingement, including high flexion and internal rotation. Femoral morphology was compared between specimens with and without labral pathology using descriptive statistics. Labral pathology was seen in 15 of 22 specimens and was located in the anterosuperior portion of the labrum. No difference existed in age, femoral neck shaft angle, anteversion, acetabular depth, head diameter, alpha angle, or beta angle between specimens with and without labral pathology. The severity of labral pathology correlated with the alpha angle of the proximal femur. This study demonstrates that damage to the labrum may occur in hips with normal proximal femur morphology. However, the findings also indicate that the presence of morphologic features that increase the risk of impingement may predispose the hip joint to a characteristic pattern or severity of labral pathology. The results confirm the importance of considering both femoral morphology and athletic-type activities of the hip when determining the mechanism responsible for injury of the acetabular labrum.

The distribution of vascular foramina at the femoral head/neck junction: implications for resurfacing arthroplasty.

Reaming for resurfacing arthroplasty may endanger the blood supply at the head-neck junction, possibly predisposing to osteonecrosis and femoral neck fracture. The current study hypothesizes that reaming endangers femoral head vasculature. Vascular foramina were identified on 16 cadaveric femora and registered on computed tomographic models. Virtual reaming was performed after templating of resurfacing components. Almost half (41.8%) of foramina was located in the anterosuperior quadrant. Loss of foramina after reaming averaged 28% (P = .03), with up to 34.6% and 33.1% loss in the anterosuperior and posterosuperior quadrants, respectively. Reaming for resurfacing arthroplasty endangers a substantial number of vascular foramina. Notching or malpositioning of components may worsen injury to the vascular supply and could subsequently increase the risk of implant failure.

The optimal skin incision for minimally invasive total hip arthroplasty performed via the anterolateral approach.

Twelve total hip arthroplasty procedures were performed in fresh cadaveric specimens via the anterolateral approach using straight 9-cm incisions placed in 2 different locations with respect to anatomical landmarks. During each procedure, the forces applied to the wound edges by each of the hip instruments and the pressures and strains generated along the wound edges were measured. Pressures ranging from 40 to 190 kPa were developed between the retractors and the wound edges during acetabular reaming and femoral rasping. The resulting strain along the wound edges averaged 28% during acetabular reaming and 34% during femoral broaching (P < .0001). Maximum strains were recorded at the ends of each incision and averaged 58% and 61%, respectively (P < .0001). These results were independent of the anatomical placement of the skin incision. In total hip arthroplasty, the mechanical trauma associated with the procedure is primarily determined by the surgical approach to the hip and the properties of the subcutaneous tissues, and not the anatomical location of the skin incision itself.

The cam impinging femur has multiple morphologic abnormalities.

This study was performed to establish whether the "cam" impinging femur has a single deformity of the head-neck junction or multiple abnormalities. Average dimensions (anteversion angle, α angle of Notzli, ß angle of Beaulé, normalized anterior head offset) were compared between normal and impinging femora. The results demonstrated that impinging femora had wider necks, larger heads, and decreased head-neck ratios. There was no difference in neck-shaft angle or anteversion angle. Forty-six percent of impinging femora had significant posterior head displacement (>2mm), which averaged 1.93 mm for the cam impinging group, and 0.78 mm for the normal group. In conclusion, surgical treatment limited to localized recontouring of the head-neck profile may fail to address significant components of the underlying abnormality.

Does acetabular retroversion affect range of motion after total hip arthroplasty?

BACKGROUND: Increasingly, acetabular retroversion is recognized in patients undergoing hip arthroplasty. Although prosthetic component positioning is not determined solely by native acetabular anatomy, acetabular retroversion presents a dilemma for component positioning if the surgeon implants the device in the anatomic position. QUESTIONS/PURPOSES: We asked (1) whether there is a difference in ROM between surface replacement arthroplasty (SRA) and THA in the retroverted acetabulum, and (2) does increased femoral anteversion improve ROM in the retroverted acetabulum? METHODS: Using a motion analysis tracking system, we determined the ROM of eight cadaveric hips and then created virtual CT-reconstructed bone models of each specimen. ROM was determined with THA and SRA systems virtually implanted with (1) the acetabular component placed in 45° abduction and matching the acetabular anteversion (average 23° ± 4°); (2) virtually retroverting the bony acetabulum 10°; and (3) after anteverting the THA femoral stem 10°. RESULTS: SRA resulted in ROM deficiencies in four of six maneuvers, averaging 25% to 29% in the normal and retroverted acetabular positions. THA restored ROM in all six positions in the normal acetabulum and in four of the six retroverted acetabula. The two deficient positions averaged 5% deficiency. THA with increased femoral stem anteversion restored ROM in five positions and showed only a 2% deficiency in the sixth position. Compared with the intact hip, ROM deficits were seen after SRA in the normal and retroverted acetabular positions and to a lesser extent for THA which can be improved with increased femoral stem anteversion. CONCLUSION: Poor ROM may result after SRA if acetabular retroversion is present.

Which procedure better restores intact hip range of motion: total hip arthroplasty or resurfacing? A combined cadaveric and computer simulation study.

Previous comparisons of hip range of motion (ROM) after THA and surface replacement arthroplasty (SRA) are inconclusive due to the lack of soft tissue considerations and dissimilar control groups. The normal ROMs of 8 intact cadaveric hips were determined by placing specimens in 6 discrete, predefined positions of rotation at a standard torque. In each position, the limiting factor of ROM, either bony impingement or soft tissue restriction, could be determined. Total hip arthroplasty and SRA components were virtually implanted, and ROM until impingement was determined. With a THA, the ROM was comparable to that of the intact hip. With an SRA, flexion (111° ± 13°) was less than for the intact hip (131° ± 6°). Surface replacement arthroplasty, but not THA, significantly decreases the ROM compared to intact hips.

Tensile strain in the anterior part of the acetabular labrum during provocative maneuvering of the normal hip.

BACKGROUND: Injury of the acetabular labrum is a well recognized cause of hip pain in the young, active patient. The exact mechanism of these injuries remains a subject of speculation, although femoroacetabular impingement and twisting maneuvers have both been proposed as critical factors. We examined the hypothesis that torsional maneuvers of the morphologically normal hip joint generate mechanical strain within the acetabular labrum, particularly in areas that are prone to injury. METHODS: Seven human cadaver specimens were loaded during five separate maneuvers with external rotation or abduction torques applied to the hip in neutral alignment and in moderate flexion or extension. Tensile strain within the acetabular labrum was measured with use of the technique of roentgen stereophotogrammetric analysis. RESULTS: Substantial tensile strains were generated within the labrum during each of the loading maneuvers, with no significant difference in strain being noted between the maneuvers. Maximum strain in the anterior part of the labrum averaged 13.6% +/- 7.8% in the axial direction and 8.4% +/- 3.0% in the circumferential direction. The highest mean and maximum strain values were found at the two o'clock position of the labrum, with the highest strain concentration at the bone-labrum interface. CONCLUSIONS: External rotation and abduction maneuvers of the morphologically normal human hip joint in moderate flexion or extension can generate substantial tensile strains in the anterior part of the acetabular labrum. This finding supports the hypothesis that injury to the anterior part of the labrum may occur from recurrent twisting or pivoting maneuvers of the hip joint in moderate flexion or extension without femoroacetabular impingement.

Backside wear of polyethylene tibial inserts: mechanism and magnitude of material loss.

BACKGROUND: Wear of the underside of modular tibial inserts (backside wear) in total knee replacements has been reported by several authors. Although, for some implant designs, this phenomenon seems to contribute to osteolysis, the actual volume of material lost through wear of the backside surface has not been quantified. This study describes the results of computerized measurements of tibial inserts of one design known to be associated with a high prevalence of backside wear in situ. METHODS: A series of retrieved total knee components of one design were examined. The duration of implantation of the retrieved components ranged from thirty-six to 146 months. Laser surface profilometry and computer-aided design software were used to develop individual three-dimensional models of each worn, retrieved tibial insert to compare with scanned unused inserts. Volumetric subtraction of both models revealed the material lost because of backside wear. RESULTS: Worn and unworn areas on the backside surface were easily identified by stereomicroscopy and laser profilometry. The computer reconstructions showed that, in all retrievals, all unworn surfaces on the nonarticulating surface lay in one plane. The average volume (and standard deviation) of the material lost because of backside wear was 925 +/- 637 mm(3) (range, 197 to 2720 mm(3)). On the basis of the time in situ for each implant, the average volumetric wear rate was 138 +/- 95 mm(3)/yr. CONCLUSIONS: The predicted volume of material removed because of backside wear is substantial and may be sufficient to induce osteolysis. Our results suggest that peg-like protrusions are not generated by the extrusion of polyethylene into screw-holes within the base-plate but by abrasion of the underside of the bearing insert, leaving the protruding pegs as the only remnants of the original surface.

Computer simulation: how can it help the surgeon optimize implant position?

Component placement critically affects the performance and longevity of total hip replacements (THRs). Because of limitations of observation and anatomic orientation imposed by the operative site, selection of the correct size, and position of the acetabular and femoral components is best done through preoperative planning. Currently, this is done by comparing two-dimensional templates of prosthetic components with clinical radiographs; however, this method has the inherent limitation that AP and lateral radiographs each provide one projection of the pelvis and the femur. Computer technology makes it possible to observe implantation of the femoral and acetabular components in three dimensions. This approach allows surgeons to template with superior accuracy, while providing an intimate view of the fit of the components in the implantation site. Additionally, computer routines can predict the functional outcome of a preoperative plan before its implementation. Restoration of leg length, center of rotation, ROM of the joint during various activities, and points of bony and prosthetic impingement can be analyzed preoperatively by the surgeon. This is a valuable tool for surgical navigation and surgeon training. With emerging technologic advances in surgical technique, computer-based preoperative planning tools should prove all the more essential to reliable component placement.

Extraarticular abrasive wear in cemented and cementless total knee arthroplasty.

In this study, we examine the contributions of periprosthetic impingement to a seldom recognized source of PE damage resulting in gouging, abrasion, and severe localized damage in cemented and cementless total knee replacement. One hundred sixty two tibial components of 34 different designs in a retrieval collection were examined. The presence and location of abrasive wear to the nonarticulating edges of the insert were measured, with representative specimens examined using SEM. Significant abrasive wear was observed in 35% of the retrievals with cemented femoral components and 25% from noncemented components. Within the group of worn inserts, abrasive scars were seen with a frequency of 75% on the extreme medial edge, 20% on the extreme lateral edge, 26% on the posteromedial edge, and 16% on the posterolateral edge. The role of extraarticular impingement in this damage mode was confirmed by examination of retrieved femoral components with overhanging cement or embedded osteophytes. In the majority of cases, this complication may be avoided by careful removal of excess cement and extracortical osteophytes.