RESUMO
Thirty-four patients with connective tissue disease used dexamethasone drops 0.1% in one eye for 6 weeks. There was a higher incidence of positive steroid response than would be expected in a normal population. Most of the male patients were responders. Care should be exercised when prescribing local steroids for these patients. Males should be offered regular screening for glaucoma.
Assuntos
Doenças do Tecido Conjuntivo/tratamento farmacológico , Dexametasona/efeitos adversos , Pressão Intraocular/efeitos dos fármacos , Malha Trabecular/efeitos dos fármacos , Adulto , Idoso , Artrite Reumatoide/tratamento farmacológico , Dexametasona/uso terapêutico , Feminino , Glaucoma/induzido quimicamente , Humanos , Masculino , Pessoa de Meia-Idade , Fatores SexuaisRESUMO
Nine percent of 215 adult patients with rheumatoid arthritis attending our clinic gave a history of leg ulcers when surveyed by a self administered questionnaire. This was over twice the frequency found in a matched control group with degenerative arthritis attending the same clinic and was a significant increase.
Assuntos
Artrite Reumatoide/complicações , Úlcera da Perna/complicações , Adulto , Idoso , Feminino , Humanos , Úlcera da Perna/epidemiologia , Masculino , Pessoa de Meia-Idade , Sistema de Registros , Reino UnidoRESUMO
A patient exhibiting typical features of classical rheumatoid arthritis and psoriatic spondylitis is described. The patient, a woman, presented at the age of 29 with an inflammatory arthritis. Twenty years later, she developed psoriasis, and after a further 3 years, she was first noted to have rheumatoid nodules and to be strongly seropositive. Now at the age of 60, she has a rigid spine with radiographic changes of spondylitis. Neither rheumatoid arthritis, nor psoriatic spondylitis can account for all the features of her disease and there is evidence to suggest that both conditions combined to damage her peripheral joints.
Assuntos
Artrite Reumatoide/complicações , Psoríase/complicações , Espondilite/complicações , Adulto , Feminino , HumanosRESUMO
The radiographic findings and clinical outcome of 54 patients having a myelogram at the request of the Department of Rheumatology over a period of five years are described. Fortynine of the patients had either clinical features of an intervertebral disc protrusion or chronic back pain of obscure aetiology. Abnormalities which could have accounted for the symptoms and signs were found in 28 of these. Although useful information was obtained in regard to therapy the investigation did not lead to surgical treatment in any of the patients without clinical evidence of lumbar root compression. No unexpected malignancies were found. Morbidity was common, but usually mild.
Assuntos
Mielografia , Doenças da Coluna Vertebral/diagnóstico por imagem , Dor nas Costas/etiologia , Feminino , Humanos , Deslocamento do Disco Intervertebral/diagnóstico por imagem , Deslocamento do Disco Intervertebral/cirurgia , Vértebras Lombares/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Mielografia/efeitos adversos , Síndromes de Compressão Nervosa/diagnóstico por imagem , Doenças da Coluna Vertebral/cirurgia , Raízes Nervosas Espinhais/diagnóstico por imagemRESUMO
Meta-iodobenzylguanidine, a guanethidine analogue, is a newly synthesised substance capable of imaging the adrenal medulla. In a woman in whom phaeochromocytoma has been diagnosed iodine-131-labelled metaiodobenzylguanidine was given intravenously; gamma-camera images showed bilateral adrenal tumours and uptake corresponding to bone and liver metastases. 131I-meta-iodobenzylguanidine is effective in localising phaeochromocytomas, and the technique is safe, specific, and non-invasive.
